Qing Guo
11 Papers
Qing Guo is an academic researcher. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 1, co-authored 1 publications.
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Papers
A Multi-Center, Randomized, Double-blinded, Placebo-controlled, Dose-ranging Study Evaluating Efficacy and Safety of Vunakizumab in Patients with Moderate-to-Severe Plaque Psoriasis.
Chunlei Zhang,Ke xiang Yan,Qingchun Diao,Qing Guo,Hongzhong Jin,Sen Yang,Xiang Chen,Tiechi Lei,Jianhua Wu,Hong Yu,Min Zeng,Xinghua Gao,Rodney Sinclair,Yi Zhu,Qian Xu,Jinhua Xu +15 more
TL;DR: Vunakizumab showed promising efficacy for moderate-to-severe plaque psoriasis, with good tolerability, warranting further investigation in larger and longer-term studies as mentioned in this paper .
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Cytotoxic CD161−CD8+ TEMRA cells contribute to the pathogenesis of systemic lupus erythematosus
Hui Xiong,Mintian Cui,Ni Kong,Jiongjie Jing,Ying-Jie Xu,Xiuting Liu,Fan Yang,Zhen Xu,Yu-Xiao Yan,Dongyang Zhao,Ziqi Zou,Meng Xia,Junjie Cen,Guo-zhen Tan,Cong Huai,Qiong Fu,Qing Guo,Kun Chen +17 more
TL;DR: Wang et al. as mentioned in this paper used single-cell RNA sequencing (scRNA-seq) of PBMCs from a SLE family pedigree (including 3 HCs and 2 SLE patients) to identify the SLE-associated CD8+ T cell subsets.
16
Enhanced Migratory Ability of Neutrophils Toward Epidermis Contributes to the Development of Psoriasis via Crosstalk With Keratinocytes by Releasing IL-17A
Xiuting Liu,Zhenrui Shi,Sijing Lu,Daniel S. Hong,Xiaoyuan Qiu,Guo-zhen Tan,Hui Xiong,Qing Guo,Liangchun Wang +8 more
TL;DR: It is found that blood neutrophils were increased in psoriasis patients, positively correlated with disease severity and highly expressed CD66b, but not CD11b and CD62L compared to healthy controls, providing a proof-of-concept that development of new drugs targeting migration of neutrophil could be a more specific and safe solution to treat Psoriasis.
CD19+CD24highCD27+ B cell and interleukin 35 as potential biomarkers of disease activity in systemic lupus erythematosus patients
Hui Xiong,Zeng-qi Tang,Ying Xu,Zhenrui Shi,Zhixuan Guo,Xiuting Liu,Guo-zhen Tan,Xuechen Ai,Qing Guo +8 more
TL;DR: Wang et al. as discussed by the authors detected the proportion of CD19+CD24highCD27+ B cells as well as IL-10 and IL-35 levels in peripheral blood of systemic lupus erythematosus patients and healthy individuals, and investigated their relations with clinical features of SLE.
New Insights into Artesunate as a Pleiotropic Regulator of Innate and Adaptive Immune Cells
TL;DR: Recent advances of how artesunate regulates innate and adaptive immune cells are summarized and its potential application in immune-related diseases is also highlighted.