Qin Pan
Wuhan University
35 Papers
154 Citations
Qin Pan is an academic researcher from Wuhan University. The author has contributed to research in topics: Immune system & Lipoarabinomannan. The author has an hindex of 17, co-authored 34 publications. Previous affiliations of Qin Pan include University of Michigan.
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Papers
Cancer stem cell vaccination confers significant antitumor immunity
Ning Ning,Qin Pan,Qin Pan,Fang Zheng,Fang Zheng,Seagal Teitz-Tennenbaum,Martin Egenti,Ji Yet,Mu Li,Christophe Ginestier,Max S. Wicha,Jeffrey S. Moyer,Mark E. Prince,Yingxin Xu,Xiao-Lian Zhang,Shiang Huang,Alfred E. Chang,Qiao Li +17 more
TL;DR: Mechanistic investigations established that CSC-primed antibodies and T cells were capable of selective targeting CSCs and conferring antitumor immunity, providing a rationale for a new type of cancer immunotherapy based on the development of CSC vaccines that can specifically target C SCs.
Aptamers That Preferentially Bind Type IVB Pili and Inhibit Human Monocytic-Cell Invasion by Salmonella enterica Serovar Typhi
Qin Pan,Xiao-Lian Zhang,Hong-Yan Wu,Pan-Wen He,Fubin Wang,Ming-Sheng Zhang,Jian-Ming Hu,Bing Xia,Jianguo Wu +8 more
TL;DR: The aptamer S-PS8.4 can serve as a tool for analysis of bacterial type IVB pilus-host cell interactions and may yield information for the development of putative new drugs against S. enterica serovar Typhi bacterial infections, useful both in prevention of infection and in therapeutic treatment.
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Antitumor effector B cells directly kill tumor cells via the Fas/FasL pathway and are regulated by IL-10
Huimin Tao,Lin Lu,Lin Lu,Yang Xia,Yang Xia,Fu Dai,Yi Wang,Yangyi Bao,Steven K. Lundy,Fumito Ito,Qin Pan,Xiao-Lian Zhang,Fang Zheng,Guoshun Shu,Bingmu Fang,Jinhong Jiang,Jianchuang Xia,Shiang Huang,Qiao Li,Qiao Li,Alfred E. Chang +20 more
TL;DR: The biological function of antitumor effector B cells, which may offer alternative cellular therapies to cancer, is defined and Trafficking of TDLN B cells in vivo suggested that they were recruited to the tumor and lung as well as secondary lymphoid organs.
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CFP10 and ESAT6 aptamers as effective Mycobacterial antigen diagnostic reagents.
TL;DR: In this article, the authors used a Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technique to screen for a functional ssDNA aptamer "antibody" that specifically bound to ESAT6-CFP10 (CE) protein.
80
A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette–Guérin Enhances Immunoprotective Effect against Tuberculosis
Xiaoming Sun,Qin Pan,Chunhui Yuan,Qilong Wang,Qilong Wang,Xiao-Lei Tang,Kan Ding,Xiang Zhou,Xiao-Lian Zhang +8 more
TL;DR: It is revealed that ManLAM-binding membrane molecule CD44 is a novel target for the enhancement of BCG immunogenicity, and BM2 has strong potential as an immune enhancer for BCG.
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