Qihui Sun
Peking Union Medical College
5 Papers
2 Citations
Qihui Sun is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Internal medicine & Medicine. The author has an hindex of 1, co-authored 2 publications.
Chat about Author
Papers
Immunosuppressive role of SPP1-CD44 in the tumor microenvironment of intrahepatic cholangiocarcinoma assessed by single-cell RNA sequencing
TL;DR: SPP1 is a prognostic marker of ICC and is associated with the genome heterogeneity, but immunosuppressive T cells in the tumor microenvironment may evade this inhibition by reducing CD44 expression.
35
•Journal Article
Co-occurrence of RUNX1 and ASXL1 mutations underlie poor response and outcome for MDS patients treated with HMAs
Ping Wu,Jianyu Weng,Minming Li,Zesheng Lu,Chengxin Deng,Qihui Sun,Ruohao Xu,Suxia Geng,Xin Du +8 more
TL;DR: RUNX1 mutations are frequently found in MDS patients with ASXL1-mutations, and Co-occurrence of RUNX1 and ASXL 1 mutations are associated with poor response to HMAs and inferior survival.
18
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer
TL;DR: LMWH could enhance ACT and ICIs-based immunotherapy by increasing lymphocyte infiltration into tumors, especially cytotoxic CD8+ T cells.
8
•Journal Article
Concurrence of Myelodysplastic syndromes and large granular lymphocyte leukemia: clinicopathological features, mutational profile and gene ontology analysis in a single center.
Kexin Ai,Minming Li,Ping Wu,Chengxin Deng,Xin Huang,Wei Ling,Ruohao Xu,Suxia Geng,Qihui Sun,Jianyu Weng,Xin Du,Xin Du +11 more
TL;DR: The concurrence of myelodysplastic syndromes (MDS) and large granular lymphocyte leukemia (LGLL) has been reported in a small group of patients and might suggest an etiologic relationship rather than a simple coincidence as mentioned in this paper.
6
Nuclear GRP78 Promotes Metabolic Reprogramming and Therapeutic Resistance in Pancreatic Ductal Adenocarcinoma.
Tiansuo Zhao,Tingting Jiang,Xiaojia Li,Shaofei Chang,Qihui Sun,Fanyang Kong,Xiangyu Kong,Fang Wei,Jie He,Jihui Hao,Keping Xie +10 more
TL;DR: Therefore, crosstalk and integration of hypoxia- and hypoglycemia-responsive signaling critically impact PDA metabolic reprogramming and therapeutic resistance.
5