Qianhao Lu
Heidelberg University
9 Papers
Qianhao Lu is an academic researcher from Heidelberg University. The author has contributed to research in topics: Cilium & Exome. The author has an hindex of 7, co-authored 9 publications.
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Papers
SMARCA4 -mutated atypical teratoid/rhabdoid tumors are associated with inherited germline alterations and poor prognosis
Martin Hasselblatt,Inga Nagel,Florian Oyen,Kerstin Bartelheim,Robert B. Russell,Ulrich Schüller,Reimar Junckerstorff,Reimar Junckerstorff,Marc K. Rosenblum,Ali H. Alassiri,Sabrina Rossi,Irene Schmid,Nicholas G. Gottardo,Helen Toledano,Elisabetta Viscardi,Milagros Balbin,Leora Witkowski,Qianhao Lu,Matthew J. Betts,William D. Foulkes,Reiner Siebert,Michael C. Frühwald,Reinhard Schneppenheim +22 more
TL;DR: Martin Hasselblatt · Inga Nagel · Florian Oyen · Kerstin Bartelheim · Robert B. Russell · Ulrich Schuller · Reimar Junckerstorff · Marc Rosenblum · Ali H. Alassiri · Sabrina Rossi · Irene Schmid · Nicholas G. Betts · William D. Foulkes · Reiner Siebert · Michael C. Fruhwald.
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DNA methylome analysis in Burkitt and follicular lymphomas identifies differentially methylated regions linked to somatic mutation and transcriptional control
Helene Kretzmer,Stephan H. Bernhart,Wei Wang,Andrea Haake,Marc A. Weniger,Anke K. Bergmann,Matthew J. Betts,Enrique Carrillo-de-Santa-Pau,Gero Doose,Jana Gutwein,Julia Richter,Volker Hovestadt,Bingding Huang,Daniel Rico,Frank Jühling,Julia Kolarova,Qianhao Lu,Christian Otto,Rabea Wagener,Judith Arnolds,Birgit Burkhardt,Alexander Claviez,HG Drexler,Sonja Eberth,Sonja Eberth,Roland Eils,Roland Eils,Paul Flicek,Siegfried Haas,Michael Hummel,Dennis Karsch,Hinrik H.D. Kerstens,Wolfram Klapper,Markus Kreuz,Chris Lawerenz,Dido Lenze,Markus Loeffler,Cristina López,Roderick A. F. MacLeod,Joost H.A. Martens,Marta Kulis,José I. Martín-Subero,Peter Möller,Inga Nagel,Simone Picelli,Inga Vater,Marius Rohde,Philip Rosenstiel,Maciej Rosolowski,Robert B. Russell,Markus Schilhabel,Matthias Schlesner,Peter F. Stadler,Monika Szczepanowski,Lorenz Trümper,Hendrik G. Stunnenberg,Ralf Küppers,Ole Ammerpohl,Peter Lichter,Reiner Siebert,Steve Hoffmann,Bernhard Radlwimmer +61 more
TL;DR: The results demonstrate a tight connection between somatic mutation, DNA methylation and transcriptional control in key B cell pathways deregulated differentially in Burkitt lymphoma and other germinal center B cell lymphomas.
CiliaCarta: An integrated and validated compendium of ciliary genes.
Teunis J. P. van Dam,Teunis J. P. van Dam,Julie Kennedy,Robin van der Lee,Erik de Vrieze,Kirsten A. Wunderlich,Suzanne Rix,Gerard W. Dougherty,Nils J. Lambacher,Nils J. Lambacher,Chunmei Li,Victor L. Jensen,Michel R. Leroux,Rim Hjeij,Nicola Horn,Yves Texier,Yasmin Wissinger,Jeroen van Reeuwijk,Gabrielle Wheway,Barbara Knapp,Jan Frederik Scheel,Brunella Franco,Dorus A. Mans,Erwin van Wijk,François Képès,Gisela G. Slaats,Grischa Toedt,Hannie Kremer,Heymut Omran,Katarzyna Szymanska,Konstantinos Koutroumpas,Marius Ueffing,Thanh-Minh T. Nguyen,Stef J.F. Letteboer,Machteld M. Oud,Sylvia E. C. van Beersum,Miriam Schmidts,Philip L. Beales,Qianhao Lu,Rachel H. Giles,Radek Szklarczyk,Robert B. Russell,Toby J. Gibson,Colin A. Johnson,Oliver E. Blacque,Uwe Wolfrum,Karsten Boldt,Ronald Roepman,Victor Hernandez-Hernandez,Martijn A. Huynen +49 more
TL;DR: It is shown that OSCP1, which has previously been implicated in two distinct non-ciliary processes, causes ciliogenic and ciliopathy-associated tissue phenotypes when depleted in zebrafish.
KIAA0556 is a novel ciliary basal body component mutated in Joubert syndrome.
Anna A. W. M. Sanders,Erik de Vrieze,Anas M. Alazami,Fatema Alzahrani,Erik B. Malarkey,Nasrin Sorusch,Lars Tebbe,Stefanie Kuhns,Teunis J. P. van Dam,Amal Alhashem,Brahim Tabarki,Qianhao Lu,Nils J. Lambacher,Julie Kennedy,Rachel V. Bowie,Lisette Hetterschijt,Sylvia E. C. van Beersum,Jeroen van Reeuwijk,Karsten Boldt,Hannie Kremer,Robert A. Kesterson,Dorota Monies,Mohamed Abouelhoda,Ronald Roepman,Martijn H. Huynen,Marius Ueffing,Robert B. Russell,Uwe Wolfrum,Bradley K. Yoder,Erwin van Wijk,Fowzan S. Alkuraya,Oliver E. Blacque +31 more
TL;DR: Functional studies in Caenorhabditis elegans nematodes and cultured human cells support a conserved ciliary role for KIAA0556 linked to microtubule regulation, and the notion that Kiaa0556 has a relatively subtle and variable cilia-related function, which is related to micro Tubule regulation is proposed.
Structural Systems Biology: Modeling Interactions and Networks for Systems Studies
Robert B. Russell,Gordana Apic,Olga V. Kalinina,Leonardo G. Trabuco,Matthew J. Betts,Qianhao Lu +5 more
- 01 Jan 2014
TL;DR: An introductory review discusses the current state of structural bioinformatics or modeling and suggests how current datasets in systems studies can profit from a better integration of predicted or known structural information.