Qiang Liu
Hirosaki University
8 Papers
33 Citations
Qiang Liu is an academic researcher from Hirosaki University. The author has contributed to research in topics: DEC1 & Cell cycle. The author has an hindex of 6, co-authored 8 publications.
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Papers
DEC1 promotes hypoxia-induced epithelial-mesenchymal transition (EMT) in human hepatocellular carcinoma cells.
Keishu Murakami,Yunyan Wu,Tadaatsu Imaizumi,Yuka Aoki,Qiang Liu,Xu Yan,Hiroko Seino,Tadashi Yoshizawa,Satoko Morohashi,Yukio Kato,Hiroshi Kijima +10 more
TL;DR: It is reported that hypoxia induced DEC1 expression in hepatocellular carcinoma (HCC) HepG2 cells, and DEC1 negatively regulated expression of HIF-1α and E-cadherin in transcriptional/translational levels.
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Podoplanin-mediated TGF-β-induced epithelial-mesenchymal transition and its correlation with bHLH transcription factor DEC in TE-11 cells
Yunyan Wu,Qiang Liu,Xu Yan,Yukio Kato,Makiko Tanaka,Sadaki Inokuchi,Tadashi Yoshizawa,Satoko Morohashi,Hiroshi Kijima +8 more
TL;DR: The correlation between podoplanin and EMT-related markers in esophageal squamous cell carcinoma (ESCC) and its linkage with the basic helix-loop-helix (bHLH) transcription factor differentiated embryonic chondrocyte (DEC) 1 and DEC2 is investigated to indicate thatpodoplanin is significantly associated with EMT of TE-11 cells, and may be directly or indirectly regulated by bHLH transcription factors DEC1 andDEC2.
Correlation between DEC1/DEC2 and epithelial‑mesenchymal transition in human prostate cancer PC‑3 cells.
Qiang Liu,Yunyan Wu,Hiroko Seino,Toshihiro Haga,Tadashi Yoshizawa,Satoko Morohashi,Hiroshi Kijima +6 more
TL;DR: Evidence is provided that DEC1 and DEC2 have opposite effects on TGF-β-induced EMT in human prostate cancer PC-3 cells, which is compatible with the upregulation of E-cadherin and downregulation of pSmad2, N-c cadherin, and vimentin.
DEC2 expression antagonizes cisplatin‑induced apoptosis in human esophageal squamous cell carcinoma
Hidenobu Sato,Yunyan Wu,Yukio Kato,Qiang Liu,Hideaki Hirai,Tadashi Yoshizawa,Satoko Morohashi,Jun Watanabe,Hiroshi Kijima +8 more
TL;DR: It is suggested that DEC2 exhibits anti-apoptotic effects in TE-11 esophageal squamous cell carcinoma cells, and inhibiting DEC2 may have therapeutic potential for the treatment of esphageal cancer, in combination with cisplatin.
Cytosolic Sensors of Viral RNA Are Involved in the Production of Interleukin-6 via Toll-Like Receptor 3 Signaling in Human Glomerular Endothelial Cells.
Qiang Liu,Tadaatsu Imaizumi,Tomomi Aizawa,Koji Hirono,Shogo Kawaguchi,Shojiro Watanabe,Koji Tsugawa,Tomoh Matsumiya,Kazuhiko Seya,Hidemi Yoshida,Hiroshi Tanaka +10 more
TL;DR: Region activation of TLR3/IFN-β/ MDA5/RIG-I/IL-6 axis due to viral and “pseudoviral” infections is involved in innate immunity and inflammatory reactions in GECs and is believed to play a pivotal role in some forms of GN.