Qian Chen
Chinese Academy of Sciences
16 Papers
Qian Chen is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Cancer research. The author has an hindex of 7, co-authored 10 publications.
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Papers
Clearable Theranostic Platform with a pH-Independent Chemodynamic Therapy Enhancement Strategy for Synergetic Photothermal Tumor Therapy
Qian Chen,Yu Luo,Wenxian Du,Zhuang Liu,Shengjian Zhang,Jiahui Yang,Heliang Yao,Tianzhi Liu,Ming Ma,Hangrong Chen +9 more
TL;DR: This work offers a universal approach to boost production •OH by a pH-independent Fenton-like reaction strategy and achieves MRI-guided synergistic enhanced photothermal-CDT for highly efficient tumor treatment.
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Photothermo-Promoted Nanocatalysis Combined with H2S-Mediated Respiration Inhibition for Efficient Cancer Therapy
TL;DR: Both in vitro and in vivo results demonstrate that the H2S‐mediated gas therapy in combination with PT enhanced ROS achieves excellent antitumor performance, which can open up a new approach for the design of gas‐mediated cancer treatment.
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Fe3O4 Mesocrystals with Distinctive Magnetothermal and Nanoenzyme Activity Enabling Self-Reinforcing Synergistic Cancer Therapy.
TL;DR: In vivo results confirm that Fe3O4 MCs can instantly initiate CDT by producing the detrimental ˙OH, and boosted reactive oxygen level not only induces cell apoptosis but also reduces the expression of heat shock protein (HSP), thus enabling low-temperature mediated MH.
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Photothermal Fenton Nanocatalysts for Synergetic Cancer Therapy in the Second Near-Infrared Window.
Haitao Sun,Yaying Zhang,Siyu Chen,Ruizhi Wang,Qian Chen,Jingchao Li,Yu Luo,Xiaolin Wang,Hangrong Chen +8 more
TL;DR: A second near-infrared (NIR-II) photothermal Fenton nanocatalyst (PFN) was developed for activatable magnetic resonance imaging (MRI)-guided synergetic photothermal therapy (PTT) and CDT of pancreatic carcinoma, providing a NIR- II photothermal nanoc atalyst for potential treatment of deep-seated tumors.
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Construction of microneedle-assisted co-delivery platform and its combining photodynamic/immunotherapy.
Shi-Xiong Chen,Ming Ma,Fengfeng Xue,Shuzhan Shen,Qian Chen,Yichen Kuang,Kaicheng Liang,Xiuli Wang,Hangrong Chen +8 more
TL;DR: A physiologically self-degradable microneedle (MN)-assisted platform is developed for combining PDT and immunotherapy via controlled co-delivery of photosensitizer (PS) and checkpoint inhibitor anti- CTLA4 antibody (aCTLA4), which generates synergistic reinforcement outcome while reducing side effects.
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