Qi Lin
Fudan University
37 Papers
64 Citations
Qi Lin is an academic researcher from Fudan University. The author has contributed to research in topics: Colorectal cancer & Medicine. The author has an hindex of 12, co-authored 37 publications.
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Papers
Bevacizumab Plus mFOLFOX6 Versus mFOLFOX6 Alone as First-Line Treatment for RAS Mutant Unresectable Colorectal Liver-Limited Metastases: The BECOME Randomized Controlled Trial.
Wentao Tang,Li Ren,Tianshu Liu,Qing-Hai Ye,Ye Wei,Guodong He,Qi Lin,Xiaoying Wang,Mingliang Wang,Fei Liang,Yuehong Cui,Jianmin Xu +11 more
TL;DR: For patients with initially unresectable RAS mutant colorectal liver metastases, bevacizumab combined with mFOLFOX6 increased the resectability of liver metastase and improved response rates and survival compared with mMFOL FOX6 alone.
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Timing of Hepatectomy for Resectable Synchronous Colorectal Liver Metastases: For Whom Simultaneous Resection Is More Suitable - A Meta-Analysis
Qingyang Feng,Ye Wei,Dexiang Zhu,Lechi Ye,Qi Lin,Wenxiang Li,Xinyu Qin,Minzhi Lyu,Jianmin Xu +8 more
TL;DR: The number of liver metastases was the major confounding factor for postoperative morbidity, especially in staged resections, and without baseline imbalances, simultaneous took no statistical significant advantage in safety and efficacy.
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Effect of Neoadjuvant Chemotherapy in Patients with Resectable Colorectal Liver Metastases
Dexiang Zhu,Yun-Shi Zhong,Ye Wei,Lechi Ye,Qi Lin,Li Ren,Qing-Hai Ye,Tianshu Liu,Jianmin Xu,Xinyu Qin +9 more
TL;DR: Not all resectable patients, only those with >2 independent risk factors, received survival benefit from neoadjuvant chemotherapy, whereas those in the high-risk group received survival Benefit (5-year survival, 39% vs. 33%, P = 0.028).
Ribosomal protein S15A promotes malignant transformation and predicts poor outcome in colorectal cancer through misregulation of p53 signaling pathway.
Jingwen Chen,Ye Wei,Qingyang Feng,Li Ren,Guodong He,Wenju Chang,Dexiang Zhu,Tuo Yi,Qi Lin,Wentao Tang,Jianmin Xu,Xinyu Qin +11 more
TL;DR: RPS15A was identified as a novel univariate prognostic factor predicting a poor outcome in CRC patients and knockeddown upregulated p53 and p21 expression whereas downregulated CDK1 expression was suggested to affect the p53 signaling pathway.
Silencing homeobox C6 inhibits colorectal cancer cell proliferation.
Meiling Ji,Qingyang Feng,Guodong He,Liangliang Yang,Wentao Tang,Xinyuan Lao,Dexiang Zhu,Qi Lin,Pingping Xu,Ye Wei,Jianmin Xu +10 more
TL;DR: HexC6 downregulation via lentivirus-mediated expression of HOXC6-targeting shRNA reduced HCT116 cell viability and colony formation in vitro, and reduced growth of subcutaneous xenografts in nude mouse, and appears to promote CRC cell proliferation and tumorigenesis through autophagy inhibition and mTOR pathway activation.
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