5 Papers
42 Citations
Qi Jin is an academic researcher from Shanghai Jiao Tong University. The author has contributed to research in topics: Ventricular fibrillation & Sotalol. The author has an hindex of 4, co-authored 5 publications.
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Papers
Intramural Foci During Long Duration Fibrillation in the Pig Ventricle
TL;DR: Recording VF with electrodes spaced sufficiently close to map activation sequences in 3D suggested mechanisms other than local reentry in the working myocardium maintain VF in the anterior LV free wall near the root of the anterior papillary muscle.
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Activation becomes highly organized during long-duration ventricular fibrillation in canine hearts.
TL;DR: In conclusion, long-duration VF in dogs frequently becomes highly organized in the subendocardium, with activation fronts arising in this region and passing intramurally toward the epicardium, even though the surface ECG continues to exhibit a disorganized pattern.
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Intracoronary infusion of catecholamines causes focal arrhythmias in pigs.
Harish Doppalapudi,Qi Jin,Derek J. Dosdall,Hao Qin,Gregory P. Walcott,Cheryl R. Killingsworth,William M. Smith,Raymond E. Ideker,Jian Huang +8 more
TL;DR: This work tested the hypothesis that elevated catecholamines alone are arrhythmogenic and confirmed the existence of acute ischemia, which causes myriad changes including increased catechlamines.
Verapamil reduces incidence of reentry during ventricular fibrillation in pigs
TL;DR: Verapamil decreased the incidence of reentry in SDVF by accelerating conduction velocity to increase the likelihood of conduction block, possibly through increased sympathetic tone, and the drug slowed activation rate and conduction Velocity after 200 s of VF, suggesting that L-type Ca(++) channels remain active and may be important in the maintenance of LDVF.
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Effects of combination of sotalol and verapamil on initiation, maintenance, and termination of ventricular fibrillation in swine hearts
TL;DR: The combination of sotalol and verapamil increased VFT but accelerated LDVF termination, which increased the VF cycle length, decreased synchronicity, increased regularity index and shortened the duration of long duration VF maintenance compared with the previous data of verAPamil alone or no drug.