Recent updates on development of protein-tyrosine phosphatase 1B inhibitors for treatment of diabetes, obesity and related disorders.

For the first time polysaccharidic ulvans have been isolated from freshwater green macroalgae Ulva flexuosa and Cladophora glomerata. One of the main components of ulvan is 3-sulfated rhamnoglucuronan showing a wide range of interesting properties and being a source of rare sugars. The production of mono- and oligo-saccharides from this polysaccharide can potentially be applied in cosmetic, pharmaceutical and food industry. In this paper a new and effective method for the isolation of ulvans from freshwater algae is described. The substance has been characterized after enzymatic hydrolysis by Fourier Transform Infrared (FT-IR) spectroscopy and elemental analysis. FT-IR spectroscopy permits identification of the band characteristic of the sulfonic acid groups, specific for this kind of polysaccharides. With increasing size of the thalli, the amount of ulvans in the algae cells increases. Hence, freshwater green macroalgae U. flexuosa and C. glomerata were found as a new source of polysaccharidic ulvans that can be considered to be potentially used in medicine, pharmacy, food and cosmetic industry.

First isolation of polysaccharidic ulvans from the cell walls of freshwater algae

Bioactive compounds from various types of sea urchin and their therapeutic effects — A review

Medical devices can offer valuable healthcare solutions due to their advanced capability in both disease diagnosis and therapy. Together with recent developments in manufacturing techniques, medical devices can now be fabricated using a diverse range of materials including metals, polymers, hydrogels, carbons, and composites. However, it is often found that living tissues are capable of sensing mismatches when material surfaces having different physical, chemical, or structural properties are interfaced with the tissue. Following this initial recognition stage, native tissues can react to the foreign surfaces by imposing several complex responses, in which unwanted reactions (e.g., inflammation, rejection, and infection) may impact the biointegration and performance of medical devices or severely affect the body and tissue functions.

Surface modification of medical devices at nanoscale—recent development and translational perspectives

In vitro characterization of bioactive compounds extracted from sea urchin (Stomopneustes variolaris) using green and conventional techniques

As a source of potent anti-inflammatory traditional medicines, the quantitative chromatographic fingerprints of sea urchin shell polysaccharides were well established via pre-column derivatization high performance liquid chromatography (HPLC) analysis. Based on the quantitative results, the content of fucose and glucose could be used as preliminary distinguishing indicators among three sea urchin shell species. Besides, the anti-inflammatory activities of the polysaccharides from sea urchin shells and their gonads were also determined. The gonad polysaccharide of Anthocidaris crassispina showed the most potent anti-inflammatory activity among all samples tested.

Polysaccharide Constituents of Three Types of Sea Urchin Shells and Their Anti-Inflammatory Activities

A 24-epibrassinolide treatment and intercropping willow with alfalfa increase the efficiency of the phytoremediation of cadmium-contaminated soil.

The invention relates to the technical field of medicine and particularly relates to sesquiterpene lactone compounds eut-Guaiane sesquiterpene with antibacterial activity and extracted from secondary metabolites of arctic eutypella funguses, and the chemical structural formula is as follows. The invention further provides a preparation method of the sesquiterpene lactone compounds and an application thereof in preparation of antibacterial agents.

Sesquiterpene lactone compounds with antibacterial activity and application thereof

Biotransformation of total coumarins of Radix Glehniae by Lecanicillium attenuatum W-1-9.

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Polysaccharide Constituents of Three Types of Sea Urchin Shells and Their Anti-Inflammatory Activities

A 24-epibrassinolide treatment and intercropping willow with alfalfa increase the efficiency of the phytoremediation of cadmium-contaminated soil.

Sesquiterpene lactone compounds with antibacterial activity and application thereof

Biotransformation of total coumarins of Radix Glehniae by Lecanicillium attenuatum W-1-9.