Pradeep Bugga
Northwestern University
6 Papers
32 Citations
Pradeep Bugga is an academic researcher from Northwestern University. The author has contributed to research in topics: Fusion protein & Covalent bond. The author has an hindex of 4, co-authored 6 publications.
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Papers
Bisboronic Acids for Selective, Physiologically Relevant Direct Glucose Sensing with Surface-Enhanced Raman Spectroscopy
Bhavya Sharma,Bhavya Sharma,Pradeep Bugga,Lindsey R. Madison,Anne Isabelle Henry,Martin G. Blaber,Nathan G. Greeneltch,Naihao Chiang,Milan Mrksich,George C. Schatz,Richard P. Van Duyne +10 more
TL;DR: The direct sensing of glucose at physiologically relevant concentrations with surface-enhanced Raman spectroscopy (SERS) on gold film-over-nanosphere (AuFON) substrates functionalized with bisboronic acid receptors demonstrates the combination of selectivity and spectral resolution that allow the sensors to resolve glucose in high backgrounds of fructose.
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Dynamic Substrates for Cell Biology.
Pradeep Bugga,Milan Mrksich +1 more
TL;DR: This short opinion reviews the strategies to manipulate ligand activity, highlights recent work that has advanced the field and discusses the applications that have been enabled, suggesting that dynamic substrates will continue to find important uses in basic and applied biointerfaces.
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Measuring Drug Metabolism Kinetics and Drug-Drug Interactions Using Self-Assembled Monolayers for Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry.
TL;DR: An approach to measure the catalytic activity of CYP2C9 using the high-throughput technique self-assembled monolayers for matrix-assisted laser desorption-ionization (SAMDI) mass spectrometry to enable drug metabolism and drug-drug interactions to be interrogated at a scale that cannot be achieved with current methods.
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Photoactivatable Reaction for Covalent Nanoscale Patterning of Multiple Proteins
TL;DR: A photoactivatable chloropyrimidine ligand was employed for covalent immobilization of SnapTag fusion proteins on self-assembled monolayers of alkanethiolates on gold to enable the preparation of surfaces with control over the density and activity of independently patterned proteins.
Sequential Photoactivation of Self-Assembled Monolayers to Direct Cell Adhesion and Migration.
Pradeep Bugga,Milan Mrksich +1 more
TL;DR: A photoactive surface chemistry that can repeatedly activate regions of the substrate for cell adhesion, spreading, and migration is reported, applied to studies of gap junction-mediated communication between two neighboring cells.
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