Ping Xu
University of Kentucky
9 Papers
68 Citations
Ping Xu is an academic researcher from University of Kentucky. The author has contributed to research in topics: Neuropilin 1 & Biology. The author has an hindex of 8, co-authored 8 publications. Previous affiliations of Ping Xu include Princeton University.
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Papers
Real-time optogenetic control of intracellular protein concentration in microbial cell cultures
TL;DR: A culturing apparatus and feedback control scheme which, in combination with an optogenetic system, allows us to generate defined perturbations in the intracellular concentration of a specific protein in microbial cell culture and is anticipate that this technology will allow for quantitative studies of biological networks as well as external tuning of synthetic gene circuits and bioprocesses.
75
Furin Processing of Semaphorin 3F Determines Its Anti-Angiogenic Activity by Regulating Direct Binding and Competition for Neuropilin
TL;DR: This work demonstrates that furin activation of the C-terminus of Sema3F produces a species that potently inhibits the binding of VEGF to neuropilin, and provides a mechanistic basis for understanding the anti-angiogenic activity of semaphorin as well as the physical interaction and competition between neuro pilin ligands.
69
The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis
Nathan A. McDonald,Yoshimasa Takizawa,Anna Feoktistova,Ping Xu,Melanie D. Ohi,Craig W. Vander Kooi,Kathleen L. Gould +6 more
TL;DR: This work investigates the function of the Schizosaccharomyces pombe Imp2 F-BAR domain in cytokinesis and finds that it is critical for Imp2's role in contractile ring constriction and disassembly, establishing that its major role is as a cell-cycle-regulated bridge between the membrane and Imp2 protein partners.
33
Visualization and Analysis of mRNA Molecules Using Fluorescence In Situ Hybridization in Saccharomyces cerevisiae
R. Scott McIsaac,Sanford J. Silverman,Lance Parsons,Ping Xu,Ryan Briehof,Megan N. McClean,David Botstein +6 more
TL;DR: A protocol for using FISH to quantify the number of mRNAs in single yeast cells using multiple single-stranded deoxyoligonucleotides conjugated to fluorescent dyes to detect nucleic acids in the native cellular environment is provided.
24
Robust network structure of the Sln1-Ypd1-Ssk1 three-component phospho-relay prevents unintended activation of the HOG MAPK pathway in Saccharomyces cerevisiae
Joseph P. Dexter,Joseph P. Dexter,Ping Xu,Jeremy Gunawardena,Megan N. McClean,Megan N. McClean +5 more
TL;DR: In this article, a three-component phospho-relay consisting of the histidine kinase Sln1, the transfer protein Ypd1, and the response regulator Ssk1 was investigated.