Ping Song
Fudan University
18 Papers
25 Citations
Ping Song is an academic researcher from Fudan University. The author has contributed to research in topics: Autophagy & Programmed cell death. The author has an hindex of 12, co-authored 18 publications. Previous affiliations of Ping Song include Ruijin Hospital.
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Papers
The role of autophagy in the neurotoxicity of cationic PAMAM dendrimers.
TL;DR: It is reported that PAMAM dendrimers induced both cytotoxicity and autophagic flux in a panel of human glioma cell lines, indicating the cytotoxic role of autophagy in neurotoxicity caused by PAM AM d endrimers and raising concerns about possible neurotoxic reaction caused by future clinical applications of PAMam dendrisers.
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Inhibition of autophagy overcomes the nanotoxicity elicited by cadmium-based quantum dots.
Jiajun Fan,Yun Sun,Shaofei Wang,Yubin Li,Xian Zeng,Zhonglian Cao,Ping Yang,Ping Song,Ziyu Wang,Zongshu Xian,Hongjian Gao,Qicheng Chen,Daxiang Cui,Dianwen Ju +13 more
TL;DR: Investigation of the underlying biological mechanisms of the toxicity of Quantum Dots CdTe/CdS 655 (QDs 655) elucidated the critical role of autophagy in QDs 655 induced toxicity, which may suggest the approach to overcome theoxicity of QDs and other nanoparticles by Autophagy inhibition.
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Targeting CD47 and Autophagy Elicited Enhanced Antitumor Effects in Non-Small Cell Lung Cancer
Xuyao Zhang,Jiajun Fan,Shaofei Wang,Yubin Li,Yubin Li,Yichen Wang,Song Li,Jingyun Luan,Ziyu Wang,Ping Song,Qicheng Chen,Wenzhi Tian,Dianwen Ju +12 more
TL;DR: The data elucidated the cytoprotective role of autophagy in CD47-targeted therapy and highlighted the potential approach for NSCLC treatment by simultaneously targeting CD47 and autophagic flux.
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Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation
Shaofei Wang,Yubin Li,Jiajun Fan,Xuyao Zhang,Jingyun Luan,Qi Bian,Tao Ding,Yichen Wang,Ziyu Wang,Ping Song,Daxiang Cui,Xiaobin Mei,Dianwen Ju +12 more
TL;DR: The finding demonstrated that IL-22 could exert favorable effects on DN via simultaneously alleviating systemic metabolic syndrome and downregulating renal NLRP3/caspase-1/IL-1β pathway, suggesting that IL -22 might have therapeutic potential for the treatment of DN.
Cationic poly(amidoamine) dendrimers induced cyto-protective autophagy in hepatocellular carcinoma cells
Yubin Li,Shaofei Wang,Ziyu Wang,Qian Xiaolu,Jiajun Fan,Xian Zeng,Yun Sun,Ping Song,Feng Meiqing,Dianwen Ju +9 more
TL;DR: It is found that PAMAM dendrimers could induce the formation of autophagosomes and the conversion of microtubule-associated protein 1 light chain 3 (LC3) in hepatocellular carcinoma HepG2 cells, while the inhibition of the Akt/mTOR and activation of the Erk 1/2 signaling pathways were involved in autophagy-induced by PAM amidoamine d endrimers.
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