Ping Peng
Tsinghua University
10 Papers
41 Citations
Ping Peng is an academic researcher from Tsinghua University. The author has contributed to research in topics: Cas9 & CRISPR. The author has an hindex of 4, co-authored 10 publications.
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Papers
Next-generation CRISPR/Cas9 transcriptional activation in Drosophila using flySAM
Yu Jia,Rong-Gang Xu,Xingjie Ren,Ben Ewen-Campen,Rajendhran Rajakumar,Jonathan Zirin,Donghui Yang-Zhou,Ruibao Zhu,Fang Wang,Decai Mao,Ping Peng,Huan-Huan Qiao,Xia Wang,Lu-Ping Liu,Lu-Ping Liu,Bowen Xu,Jun-Yuan Ji,Qingfei Liu,Jin Sun,Norbert Perrimon,Norbert Perrimon,Jian-Quan Ni +21 more
TL;DR: FlySAM greatly improves on existing in vivo CRISPRa techniques in terms of potency, scalability, and ease of use, and provides a simple and general method for conducting overexpression experiments and screens.
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Drosulfakinin signaling in fruitless circuitry antagonizes P1 neurons to regulate sexual arousal in Drosophila.
Shun-Fan Wu,Chao Guo,Huan Zhao,Mengshi Sun,Jie Chen,Caihong Han,Qionglin Peng,Huan-Huan Qiao,Ping Peng,Yan Liu,Shengzhan D. Luo,Yufeng Pan,Yufeng Pan +12 more
TL;DR: The authors identified inhibitory Drosulfakinin-expressing neurons that interact with P1 neurons in an experience-dependent manner, and oppositely regulate male sex drive.
An efficient and multiple target transgenic RNAi technique with low toxicity in Drosophila.
Huan-Huan Qiao,Fang Wang,Rong-Gang Xu,Jin Sun,Ruibao Zhu,Decai Mao,Xingjie Ren,Xia Wang,Yu Jia,Ping Peng,Da Shen,Lu-Ping Liu,Zhijie Chang,Guirong Wang,Shao Li,Jun-Yuan Ji,Qingfei Liu,Jian-Quan Ni,Jian-Quan Ni +18 more
TL;DR: A next generation transgenic RNAi system with reduced leakiness of expression and simultaneous knockdown is developed and versatility is increased which can simultaneously knock down multiple genes in one step.
Large-Scale Transgenic Drosophila Resource Collections for Loss- and Gain-of-Function Studies.
Jonathan Zirin,Yanhui Hu,Lu-Ping Liu,Donghui Yang-Zhou,Ryan Colbeth,Dong Yan,Benjamin Scott Ewen-Campen,Rong Tao,Eric Vogt,Sara VanNest,Cooper Cavers,Christians Villalta,Aram Comjean,Jin Sun,Xia Wang,Yu Jia,Ruibao Zhu,Ping Peng,Jinchao Yu,Da Shen,Yuhao Qiu,Limmond Ayisi,Henna Ragoowansi,Ethan Fenton,Senait Efrem,Annette L. Parks,Kuniaki Saito,Shu Kondo,Liz Perkins,Stephanie E. Mohr,Jian-Quan Ni,Norbert Perrimon,Norbert Perrimon +32 more
TL;DR: The Transgenic RNAi Project (TRiP), a Drosophila melanogaster functional genomics platform at Harvard Medical School, was initiated in 2008 to generate and distribute a genome-scale collection of RNA interference (RNAi) fly stocks, and this work presents an update on these libraries of publicly available RNAi and CRISPR fly stocks.
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flySAM Transgenic CRISPRa System Manual.
Yu Jia,Da Shen,Xia Wang,Jin Sun,Ping Peng,Rong-Gang Xu,Bowen Xu,Jian-Quan Ni,Jian-Quan Ni +8 more
- 20 Jan 2019
TL;DR: This protocol describes how to build an effective and convenient targeting activator system, flySAM, to activate endogenous genes in Drosophila melanogaster based on the structure-guided engineering of CRISPR-Cas9 complex.
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