Ping Lu
Tufts University
5 Papers
4 Citations
Ping Lu is an academic researcher from Tufts University. The author has contributed to research in topics: Regulator of G protein signaling & Nitric oxide. The author has an hindex of 3, co-authored 5 publications.
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Papers
High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase
Ivan S. Yuhanna,Yan Zhu,Blair E. Cox,Lisa Hahner,Sherri Osborne-Lawrence,Ping Lu,Yves L. Marcel,Richard G.W. Anderson,Michael E. Mendelsohn,Helen H. Hobbs,Philip W. Shaul +10 more
TL;DR: It is shown that HDL stimulates endothelial nitric oxide synthase (eNOS) in cultured endothelial cells through a process that requires ApoA-I binding, and the resulting increase in nitric-oxide production might be critical to the atheroprotective properties of HDL and Apo-I.
788
Abnormal Vascular Function and Hypertension in Mice Deficient in Estrogen Receptor β
Yan Zhu,Zhao Bian,Ping Lu,Richard H. Karas,Lin Bao,Daniel H. Cox,Jeffrey B. Hodgin,Philip W. Shaul,Peter Thorén,Oliver Smithies,Jan-Åke Gustafsson,Michael E. Mendelsohn +11 more
TL;DR: An essential role for ERβ in the regulation of vascular function and blood pressure is supported by show that vascular smooth muscle cells and blood vessels from estrogen receptor β (ERβ)–deficient mice exhibit multiple functional abnormalities.
519
Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure
K. Mary Tang,Guang-rong Wang,Ping Lu,Richard H. Karas,Mark Aronovitz,Scott P. Heximer,Kevin M. Kaltenbronn,Kendall J. Blumer,David P. Siderovski,Yan Zhu,Michael E. Mendelsohn +10 more
TL;DR: It is shown that RGS-2 is required for normal vascular function and blood pressure and is a new drug development target for hypertension.
411
Endothelial dysfunction and systemic hypertension by selective cGMP-dependent protein kinase I inhibition using novel cell-penetrating peptide delivered in vivo
Kian Keong Poh,Ping Lu,Gangjian Qin,Marcy Silver,Douglas W. Losordo,Michael E. Mendelsohn,Yan Zhu,Yan Zhu +7 more
TL;DR: It is demonstrated that highly specific peptide inhibitor of cGPK induced adult murine hypertension through inhibition of nitric oxide mediated relaxation.
3
•Journal Article
Erratum: Regulator of G-protein signaling-2 mediates vascular smooth muscle relaxation and blood pressure (Nature Medicine (2003) 9 (1506-1512))
K. Mary Tang,Guang Rong Wang,Ping Lu,Richard H. Karas,Mark Aronovitz,Scott P. Heximer,Kevin M. Kaltenbronn,Kendall J. Blumer,David P. Siderovski,Yan Zhu,Michael E. Mendelsohn +10 more
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