Ping Li
8 Papers
Ping Li is an academic researcher. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 3, co-authored 8 publications.
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Papers
microRNA-145-5p inhibits prostate cancer bone metastatic by modulating the epithelial-mesenchymal transition
Bingfeng Luo,Yuan Yuan,Yifei Zhu,Songwu Liang,Runan Dong,J. Hou,Ping Li,Yaping Xing,Zhenquan Lu,Richard Lo,Guan-Ming Kuang +10 more
TL;DR: It was found that miRNA-145-5p mediated the epithelial-mesenchymal transition (EMT) and induced apoptosis in Pca bone metastasis, raising the possibility of a novel target for treating Pca with bone metastases.
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An mTOR and DNA-PK dual inhibitor CC-115 hinders non-small cell lung cancer cell growth
TL;DR: In this article , the authors evaluated CC-115's activity in different human non-small cell lung cancer (NSCLC) cells and A549 cells and found that the dual inhibitor was unable to induce significant cytotoxic and pro-apoptotic activity in the lung epithelial cells.
Strategies to induce natural killer cell tolerance in xenotransplantation
Kevin Lopez,Arthur A Cross-Najafi,Kristine Farag,Benjamin Obando,Deepthi Thadasina,Abdulkadir Isidan,Yujin Park,Wenjun Zhang,Burcin Ekser,Ping Li +9 more
TL;DR: The key receptor-ligand interactions that determine the NK cell response to target cells are highlighted, focusing on the regulation of NK cell activating receptor (NKG2D, DNAM1) and inhibitory receptor (KIR2DL1-4, NKG2A, and LIR-1) signaling pathways.
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CDK4/6 inhibition enhances oncolytic virus efficacy by potentiating tumor-selective cell killing and T cell activation in refractory glioblastoma.
Deyin Guo,Jingshu Xiao,Jiaming Liang,Junjie Fan,Panpan Hou,Xiao-Dong Li,Haipeng Zhang,Kai Li,Lang Bu,Ping Li,Miao He,Yongheng Zhong,Liping Guo,Penghui Jia,Qiaoqiao Xiao,Junyu Wu,Hong Peng,Chunmei Li,Fan Xing +18 more
TL;DR: A dual-step drug screen for identifying chemical enhancers of oncolytic virus in GBM found an inhibitor of CDK4/6 was identified as the top enhancer, selectively increasing potency of two OV strains, VSVΔ51 and Zika virus.
The mitochondrial RNA polymerase POLRMT promotes skin squamous cell carcinoma cell growth
TL;DR: In this article , RNA polymerase mitochondrial (POLRMT) expression and potential biological functions in skin squamous cell carcinoma (SCC) were explored, and it was shown that over-expressed POLRMT increased mtDNA transcription and augmented skin SCC cell growth.