Ping Li
Zhengzhou University
7 Papers
50 Citations
Ping Li is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Apoptosis & Chalcone. The author has an hindex of 5, co-authored 7 publications.
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Papers
Molecular diversity of trimethoxyphenyl-1,2,3-triazole hybrids as novel colchicine site tubulin polymerization inhibitors.
TL;DR: Trimethoxyphenyl-1,2,3-triazole containing the coumarin fragement 19c displayed better antiproliferative activity results with IC50 values from 0.13 μM to 1.74 μM than anticancer drug colchicine.
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Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues - Chlorpyrifos and Carbofuran via oxidative stress.
TL;DR: The results showed CPF and CBF have a synergistic neurotoxicity on neural cell SK-N-SH and the toxicity remained on long-term low-dose condition.
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Design and synthesis of formononetin-dithiocarbamate hybrids that inhibit growth and migration of PC-3 cells via MAPK/Wnt signaling pathways.
Dong-Jun Fu,Zhang Li,Jian Song,Ruo-Wang Mao,Ruo-Han Zhao,Ying-Chao Liu,Yu-Hui Hou,Jia-Huan Li,Jia-Jia Yang,Cheng-Yun Jin,Ping Li,Xiaolin Zi,Hong-Min Liu,Sai-Yang Zhang,Yan-Bing Zhang +14 more
TL;DR: A series of novel formononetin-dithiocarbamate derivatives were designed, synthesized and evaluated for antiproliferative activity against three selected cancer cell line (MGC-803, EC-109, PC-3) as mentioned in this paper.
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Bioactive heterocycles containing a 3,4,5-trimethoxyphenyl fragment exerting potent antiproliferative activity through microtubule destabilization.
Dong-Jun Fu,Jia-Jia Yang,Ping Li,Yu-Hui Hou,Sheng-Nan Huang,Matthew Tippin,Victor Pham,Liankun Song,Xiaolin Zi,Wei-Li Xue,Li-Rong Zhang,Sai-Yang Zhang +11 more
TL;DR: 4d acted as a novel tubulin polymerization inhibitor binding to colchicine site with an IC50 value of 3.35 μM and could change the membrane potential (ΔΨ) of the mitochondria against MGC-803 cells.
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Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase.
Dong-Jun Fu,Jia-Huan Li,Jia-Jia Yang,Ping Li,Yan-Bing Zhang,Si-Meng Liu,Zhong-Rui Li,Sai-Yang Zhang +7 more
TL;DR: Results indicated that 12d is a promising lead compound and deserves further investigation for prevention and treatment of human prostate cancer.
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