Ping Li
Sun Yat-sen University
5 Papers
7 Citations
Ping Li is an academic researcher from Sun Yat-sen University. The author has contributed to research in topics: RNase P & Ubiquitin ligase. The author has an hindex of 2, co-authored 5 publications.
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Papers
Non-Structural Protein 5 of Zika Virus Interacts with p53 in Human Neural Progenitor Cells and Induces p53-Mediated Apoptosis
Ping Li,Hualian Jiang,Hong Peng,Wei-jie Zeng,Yongheng Zhong,Miao He,Luyang Xie,Junhai Chen,Deyin Guo,Junyu Wu,Chunmei Li +10 more
TL;DR: In this article, the effects of ZIKV-encoded proteins in the activation of p53 signaling pathway were investigated, and it was found that the nonstructural protein 5 (NS5) of zika virus most significantly activated the transcription of the p53 target genes.
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Meta-Transcriptomic Analysis Reveals the Virome and Viral Genomic Evolution of Medically Important Mites.
Liping Guo,Xiaoyu Lu,Xue Liu,Ping Li,Junyu Wu,Fan Xing,Hong Peng,Xiaojun Xiao,Mang Shi,Zhigang Liu,Xiao Dong Li,Deyin Guo +11 more
TL;DR: A total transcriptomics approach was used to characterize and compare the complete RNA virome within mites that are relevant to human health and diseases, and revealed a large diversity, a high abundance, and a flexible genomic evolution for these viruses.
The Ubiquitin E3 Ligase Parkin Inhibits Innate Antiviral Immunity Through K48-Linked Polyubiquitination of RIG-I and MDA5
Lang Bu,Huan Wang,Panpan Hou,Shuting Guo,Miao He,Jingshu Xiao,Ping Li,Yongheng Zhong,Penghui Jia,Yuanyuan Cao,Guanzhan Liang,Chenwei Yang,Lang Chen,Deyin Guo,Chunmei Li +14 more
TL;DR: It is demonstrated that Parkin limits RLR-triggered innate immunity activation, suggesting Parkin as a potential therapeutic target for the control of viral infection.
Endogenous reverse transcriptase and RNase H-mediated antiviral mechanism in embryonic stem cells.
Junyu Wu,Chunyan Wu,Fan Xing,Liu Cao,Wei-jie Zeng,Liping Guo,Ping Li,Yongheng Zhong,Hualian Jiang,Manhui Luo,Guang Shi,Lang Bu,Yanxi Ji,Panpan Hou,Hong Peng,Junjiu Huang,Chunmei Li,Deyin Guo +17 more
TL;DR: In this paper, a nucleic acid-based antiviral system that exists in mouse embryonic stem cells (mESCs), which suppresses RNA virus infection by DNA-mediated RNA cleavage was reported.