Heterocyclic compounds are a class of compounds of natural origin with favorable properties and hence have major pharmaceutical significance. They have an exceptional adroitness favoring their use as diverse smart biomimetics, in addition to possessing an active pharmacophore in a complex structure. This has made them an indispensable motif in the drug discovery field. Heterocyclic compounds are usually classified according to the ring size, type, and the number of heteroatoms present in the ring. Among different heterocyclic ring systems, nitrogen heterocyclic compounds are more abundant in nature. They also have considerable pharmacological significance. This review highlights recent pioneering studies in the biological assessment of nitrogen-containing compounds, namely: triazoles, tetrazoles, imidazole/benzimidazoles, pyrimidines, and quinolines. It explores publications between April 2020 and February 2022 and will benefit researchers in medicinal chemistry and pharmacology. The present work is organized based on the size of the heterocyclic ring.

/pdf/an-overview-of-the-biological-evaluation-of-selected-1dhi6e4s.pdf

An Overview of the Biological Evaluation of Selected Nitrogen-Containing Heterocycle Medicinal Chemistry Compounds

The world’s biodiesel increasing production is leading to the accumulation of its main by-product, crude glycerol, with almost no economic value, which valorization is crucial to increase biodiesel...

A review of aerobic glycerol oxidation processes using heterogeneous catalysts: a sustainable pathway for the production of dihydroxyacetone

Rapid, Metal-Free, Catalytic Conversion of Glycerol to Allyl Monomers and Polymers

A process for catalytic production of dihydroxyacetone through glycerol oxidation and dihydroxyacetone purification by chromatographic processes is herein presented. Glycerol oxidation over commerc...

Dihydroxyacetone Production: From Glycerol Catalytic Oxidation with Commercial Catalysts to Chromatographic Separation

Glycerol oxidation was investigated using as catalyst an acid zeolite (H-ZSM-5) impregnated with different contents of Pt (1 and 3 wt%), and H2O2 and air as oxidants. Catalysts were characterized by XRD, XRF, FT-IR, 27Al MAS NMR, N2 adsorption, NH3-TPD, XPS and TEM. After calcination, catalysts were reduced at 1000 °C under H2 and this treatment lead to some dealumination that influenced catalyst acidity. The influence of acidity was evaluated in glycerol oxidation. All tested catalysts were able to oxidize glycerol, and the main products were 1,3-dihydroxyacetone, glyceric acid and glyceraldehyde.

Effect of Pt/HZSM-5 dealumination by high temperature reduction on glycerol oxidation

An Efficient Chemical Conversion of Glycerol to Dihydroxyacetone

Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders.

The present invention relates to oxidative chemical methodologies for the selective transformation of glycerol (1,2,3-propanetriol, glycerin) into 1,3-dihydroxy-2-propanone (1,3 -Dihydroxyacetone, DHA), by using oxidizing agents available at low cost such as sources of positive halogen used in the presence of Lewis acids as catalysts.

Method for the selective oxidation of glycerol to dihydroxyacetone

Handle everyday research tasks with reliable, citation-backed results

Your personal Research Agent to handle research tasks with citation-backed results

Popular Tasks used by Researchers

How can I help with your research?

Meet SciSpace

Get more enhanced response by uploading the PDFs you want me to reference.

No relevant PDFs in your library

SciSpace is the AI research assistant for academics. Run systematic literature reviews on 280M+ papers, and write papers with cited sources. Trusted by 1M+ students, PhDs & researchers.

SciSpace | AI for Research

Analyze PDFs

Code & Manuscripts

Funding & Grants

Literature & Patents

Medical & Clinical Data

Systematic Review

Visualize & Present

Web & Data

Build a Google Scholar-like website for your research.

Build a website

Create charts and images for your research

Create a Chart

Write a paper for submission to a journal

Draft a manuscript

Patent Search

Design eye-catching scientific posters in minutes.

Scientific Poster Generation

Systematic Literature Review

One task is running at the moment. Your messages will be shown right after.

Drag and drop or click here to browse

Loved by <highlight>1 million+</highlight> researchers

Extract a list of specific topics and their sources from unstructured text

Topics

Compare and analyze relevant papers that matches with your search

Papers

Get insights from PDFs and bookmarked papers from your library

My library

Recent searches

Try searching for:

Catch AI-generated content in scholarly and non-scholarly content

{ai} Detector

Ai Writer

Get PDF Summaries, highlighted text explanations 

Chat with PDF

Effortlessly create in-text citations and bibliographies in APA and 2,500 other formats

Citation generator

Get explanations, summaries, and answers on academic papers

Ease up your research workflow with {scispace}'s cohort of exciting AI tools

Elevate your academic writing skills and convey your ideas the way you want

Paraphraser

Explore our range of reading and writing tools

Your file is being prepared and should be ready in a few minutes. If it's a large file, it might take a bit longer. You can close this window, and we'll email you the file when it's done.

You have reached a maximum limit of <strong>{limit}</strong> columns in the table. Remove at least <strong>1</strong> column to add or create another one.

Pietro Spanu

Author Tools

Chat about Author

Papers

An Efficient Chemical Conversion of Glycerol to Dihydroxyacetone

Design, synthesis and biological evaluation of 1,5-disubstituted α-amino tetrazole derivatives as non-covalent inflammasome-caspase-1 complex inhibitors with potential application against immune and inflammatory disorders.

Method for the selective oxidation of glycerol to dihydroxyacetone