Pietro Giacinto
University of Bologna
14 Papers
39 Citations
Pietro Giacinto is an academic researcher from University of Bologna. The author has contributed to research in topics: Enantioselective synthesis & Catalysis. The author has an hindex of 8, co-authored 14 publications.
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Papers
Gold(I)‐Catalyzed Dearomative [2+2]‐Cycloaddition of Indoles with Activated Allenes: A Combined Experimental–Computational Study
Riccardo Ocello,Assunta De Nisi,Minqiang Jia,Qing-Qing Yang,Magda Monari,Pietro Giacinto,Andrea Bottoni,Gian Pietro Miscione,Gian Pietro Miscione,Marco Bandini +9 more
TL;DR: The computational (DFT) investigation has fully elucidated the reaction mechanism providing clear evidence for a two-step reaction, and two parallel reaction pathways explain the regioisomeric products obtained under kinetic and thermodynamic conditions.
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Cl(−) Exchange SN2 Reaction inside Carbon Nanotubes: C–H···π and Cl···π Interactions Govern the Course of the Reaction
TL;DR: In this paper, the carbon nanotube (CNT)-confined chloride exchange SN2 reaction for methyl chloride has been examined using either a full quantum mechanical (QM) DFT approach based on the M06-2X functional or a hybrid approach where a (6,6) CNT is satisfactorily described by the molecular mechanics (MM) UFF force field and the substrate by the MCUFF functional.
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Gold(I)‐Assisted α‐Allylation of Enals and Enones with Alcohols
Marco Michele Mastandrea,Niall Mellonie,Pietro Giacinto,Alba Collado,Steven P. Nolan,Steven P. Nolan,Gian Pietro Miscione,Gian Pietro Miscione,Andrea Bottoni,Marco Bandini +9 more
TL;DR: DFT calculations support the role of an α-gold(I) enal/enone as the active nucleophilic species in the intermolecular α-allylation of enals and enones.
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CNT-Confinement Effects on the Menshutkin SN2 Reaction: The Role of Nonbonded Interactions.
TL;DR: It is found that the CNT significantly lowers the activation barrier with respect to the hypothetical gas-phase reaction and the simple Qeq formalism does not describe properly the effect of CNT polarization in the presence of the net charge separation featuring the final product.
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Covalent or Non-Covalent? A Mechanistic Insight into the Enantioselective Brønsted Acid Catalyzed Dearomatization of Indoles with Allenamides
TL;DR: In this article, the reaction mechanism of the enantioselective Brønsted acid catalyzed dearomatization of C(2),C(3)disubstituted indoles with allenamides is investigated by means of density functional theory (DFT) calculations and ESI-MS analysis.
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