Pietro Cicuta
University of Cambridge
204 Papers
1K Citations
Pietro Cicuta is an academic researcher from University of Cambridge. The author has contributed to research in topics: Computer science & Medicine. The author has an hindex of 42, co-authored 181 publications. Previous affiliations of Pietro Cicuta include University of British Columbia & University of Milan.
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Papers
Critical fluctuations in plasma membrane vesicles.
Sarah L. Veatch,Pietro Cicuta,Prabuddha Sengupta,Aurelia R. Honerkamp-Smith,David Holowka,Barbara Baird +5 more
TL;DR: Critical behavior in giant plasma membrane vesicles that are isolated directly from living cells suggest that the compositions of mammalian plasma membranes are tuned to reside near a miscibility critical point and that heterogeneity corresponding to < 50 nm-sized compositional fluctuations are present in GPMV membranes at physiological temperatures.
529
Exploring Automatic Diagnosis of COVID-19 from Crowdsourced Respiratory Sound Data
Chloë Brown,Jagmohan Chauhan,Andreas Grammenos,Jing Han,Apinan Hasthanasombat,Dimitris Spathis,Tong Xia,Pietro Cicuta,Cecilia Mascolo +8 more
TL;DR: The results show that even a simple binary machine learning classifier is able to classify correctly healthy and COVID-19 sounds, and opens the door to further investigation of how automatically analysed respiratory patterns could be used as pre-screening signals to aid CO VID-19 diagnosis.
Line Tensions, Correlation Lengths, and Critical Exponents in Lipid Membranes Near Critical Points
Aurelia R. Honerkamp-Smith,Pietro Cicuta,Marcus D. Collins,Sarah L. Veatch,Marcel den Nijs,Michael Schick,Sarah L. Keller +6 more
TL;DR: In this article, the temperature dependence of line tension between liquid domains and of fluctuation correlation lengths in lipid membranes was quantitatively evaluated to obtain a critical exponent, nu = 1.2 +/- 0.2.
377
Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex
Si Ming Man,Lee Hopkins,Eileen Nugent,Susan Cox,Ivo M. Glück,Panagiotis Tourlomousis,John A. Wright,Pietro Cicuta,Tom P. Monie,Clare E. Bryant +9 more
TL;DR: The data reveal the spatial localization of different components of the inflammasome and how different members of the NLR family cooperate to drive robust IL-1β processing within the Salmonella-infected cell and to regulate the bacterial burden in mice.
Diffusion of liquid domains in lipid bilayer membranes.
TL;DR: Diffusion coefficients of micron-scale liquid domains in giant unilamellar vesicles of phospholipids and cholesterol are reported and mechanisms of domain diffusion are found which are consistent with membrane- dominated drag in viscous L(o) phases and bulk-dominated drag for less viscousL(alpha) phases.
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