Pierre Moreau
University of Eastern Finland
114 Papers
1.7K Citations
Pierre Moreau is an academic researcher from University of Eastern Finland. The author has contributed to research in topics: Endothelin receptor & Angiotensin II. The author has an hindex of 38, co-authored 103 publications. Previous affiliations of Pierre Moreau include Kuwait University & University of Zurich.
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Papers
Tetrahydrobiopterin alters superoxide and nitric oxide release in prehypertensive rats.
Francesco Cosentino,S Patton,Livius V. d’Uscio,Ernst R. Werner,Gabriele Werner-Felmayer,Pierre Moreau,T Malinski,Thomas F. Lüscher +7 more
TL;DR: Dysfunctional cNOS may be a source of O2- in prehypertensive SHR and contribute to the development of hypertension and its vascular complications.
Angiotensin II Increases Tissue Endothelin and Induces Vascular Hypertrophy
Pierre Moreau,Livius V. d’Uscio,Sidney G. Shaw,Hiroyuki Takase,Matthias Barton,Thomas F. Lüscher +5 more
TL;DR: In this paper, the endogenous effect of endothelin-1 on angiotensin II-induced hypertrophy of small arteries in vivo has been investigated and it was shown that endothein-1 increased media thickness, media/lumen ratio, and cross-sectional area of basilar and small mesenteric arteries.
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Effect of age on kinetics of nitric oxide release in rat aorta and pulmonary artery.
M. R. Tschudi,Matthias Barton,N. A. Bersinger,Pierre Moreau,Francesco Cosentino,G Noll,T Malinski,Thomas F. Lüscher +7 more
TL;DR: Ageing specifically reduces initial rate and peak concentrations of endothelial NO release from aorta but not pulmonary artery indicating reduced NO production, which appears important as NO plays a protective role by preventing vasoconstriction, thrombosis and atherosclerosis.
Evolution and modulation of age-related medial elastocalcinosis: Impact on large artery stiffness and isolated systolic hypertension
TL;DR: The concept that elastocalcinosis is a valuable therapeutic target is put forward and evidence that this process can be prevented and reversed pharmacologically is presented.
Angiotensin II increases vascular and renal endothelin-1 and functional endothelin converting enzyme activity in vivo: role of ETA receptors for endothelin regulation.
TL;DR: Angiotensin II (Ang II)-stimulated expression of endothelin-1 (ET-1) mRNA is blocked by ETAantagonists in vitro and in WKY rats in vivo, investigating vascular and renal ET-1 protein expression, functionalendothelin converting enzyme (ECE) activity, and clearance of125IET- 1.
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