Phyllis Gamble
University of Texas Medical Branch
19 Papers
104 Citations
Phyllis Gamble is an academic researcher from University of Texas Medical Branch. The author has contributed to research in topics: Offspring & Preeclampsia. The author has an hindex of 8, co-authored 19 publications.
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Papers
The effect of prenatal pravastatin treatment on altered fetal programming of postnatal growth and metabolic function in a preeclampsia-like murine model.
Mollie McDonnold,Esther Tamayo,Talar Kechichian,Phyllis Gamble,Monica Longo,Gary D.V. Hankins,George R. Saade,Maged M. Costantine +7 more
TL;DR: Preeclampsia alters postnatal growth and metabolic function in the adult offspring in this animal model and maternal therapy with prav prevents some of these alterations in the offspring.
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Characterization of a murine model of fetal programming of atherosclerosis
Nima Goharkhay,Elena Sbrana,Phyllis Gamble,Esther Tamayo,Ancizar Betancourt,Karina Villarreal,Gary D.V. Hankins,George R. Saade,Monica Longo +8 more
TL;DR: Investigation of cross-bred mice found increased total cholesterol levels and incidence of atherosclerosis in offspring born to hypercholesterolemic mothers as compared with genomically similar animals born to wild-type mothers.
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Prepregnancy obesity and sFlt1-induced preeclampsia in mice: Developmental programming model of metabolic syndrome
Egle Bytautiene,Esther Tamayo,Talar Kechichian,Nathan Drever,Phyllis Gamble,Gary D.V. Hankins,George R. Saade +6 more
TL;DR: Exposure to maternal prepregnancy obesity and sFlt1-induced preeclampsia alter the offspring's blood pressure, metabolic, inflammatory, and atherosclerotic profiles later in life.
30
Sex-specific effects of nicotine exposure on developmental programming of blood pressure and vascular reactivity in the C57Bl/6J mouse.
Karin A. Fox,Monica Longo,Esther Tamayo,Phyllis Gamble,Michel Makhlouf,Julio Mateus,George R. Saade +6 more
TL;DR: Perinatal nicotine exposure has an impact on the developmental programming of future cardiovascular health, with adverse effects more evident in female offspring.
17
Is There a causal relation between maternal acetaminophen administration and ADHD
Antonio F. Saad,Shruti Hegde,Talar Kechichian,Phyllis Gamble,Mahbubur Rahman,Sonja J. Stutz,Noelle C. Anastasio,Wael Alshehri,Jun Lei,Susumu Mori,Bridget Kajs,Kathryn A. Cunningham,George R. Saade,Irina Burd,Maged M. Costantine +14 more
TL;DR: This study refutes that hypothesis that prenatal exposure to APAP causes hyperkinetic dysfunction in mouse offspring, using a murine model, and recommends that results should be taken with caution when compared to the reported clinical data.