Philippe Urban
University of Toulouse
55 Papers
1.1K Citations
Philippe Urban is an academic researcher from University of Toulouse. The author has contributed to research in topics: Yeast & Saccharomyces cerevisiae. The author has an hindex of 25, co-authored 49 publications. Previous affiliations of Philippe Urban include Ludwig Maximilian University of Munich & Pierre-and-Marie-Curie University.
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Papers
Cloning, Yeast Expression, and Characterization of the Coupling of Two Distantly Related Arabidopsis thalianaNADPH-Cytochrome P450 Reductases with P450 CYP73A5
TL;DR: Biochemical characterization of the Arabidopsis ATR1/CYP73A5 and ATR2-1/Yeast systems demonstrates that the two distantly relatedArabidopsis reductases similarly support the first oxidative step of the phenylpropanoid general pathway.
358
On the Redox Potentials of Ubiquinone and Cytochrome b in the Respiratory Chain
TL;DR: The present study attempts to measure a redox potential of ubiquinone in a submitochondrial respiratory chain preparation utilizing equilibration of ubiqu inone with an appropriate substrate couple such as succinate/fumarate, a procedure which has been applied for this purpose in earlier studies.
188
Localization of I2-Imidazoline Binding Sites on Monoamine Oxidases
F. Tesson,Isabelle Limon-Boulez,Philippe Urban,Magda Puype,Jol Vandekerckhove,Isabelle Coupry,Denis Pompon,Angelo Parini +7 more
TL;DR: Results show definitely that I2BS is located on both MAO-A and -B, and the fact that I 2BS ligands inhibited MAO activity independently of the interaction with the catalytic region suggests that I1BS might be a previously unknown MAO regulatory site.
177
Enhanced in vivo monooxygenase activities of mammalian P450s in engineered yeast cells producing high levels of NADPH-P450 reductase and human cytochrome b5
TL;DR: In a strain containing optimized amounts of Hb5 and Yred, human P450 3A4-specific testosterone-6 beta-hydroxylase activity can be enhanced as much as 73-fold in comparison with the activity observed in a wild-type strain.
167
Maximizing the expression of mammalian cytochrome P-450 monooxygenase activities in yeast cells.
TL;DR: Results demonstrate that the low amounts of endogenous NADPH-cytochrome P-450 reductase and cytochrome b5 which are naturally present, are limiting for the heterologous monooxygenase activities.
116