Philippe Gripon
University of Rennes
3 Papers
45 Citations
Philippe Gripon is an academic researcher from University of Rennes. The author has contributed to research in topics: Gene & Infectivity. The author has an hindex of 3, co-authored 3 publications.
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Papers
Hepatocyte iron loading capacity is associated with differentiation and repression of motility in the HepaRG cell line.
Marie-Bérengère Troadec,Denise Glaise,Guillaume Lamirault,Martine Le Cunff,Emilie Guérin,Nolwenn Le Meur,Lénaïck Détivaud,Pierre Zindy,Patricia Leroyer,Isabelle Guisle,Hélène Duval,Philippe Gripon,Nathalie Théret,Karim Boudjema,Christiane Guguen-Guillouzo,Pierre Brissot,Jean J. Leger,Olivier Loréal +17 more
TL;DR: It is demonstrated that HepaRG hepatocyte iron loading capacity occurred both with the repression of genes involved in cell motility, signal transduction, and biosynthesis and with the appearance of genes linked to lipid metabolism and immune response.
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Entry of pseudotyped hepatitis C virus into primary human hepatocytes depends on the scavenger class B type I receptor.
TL;DR: It is shown that SRBI also plays an essential role in HCV entry into primary human hepatocytes with two distinct approaches: gene extinction and antibodies neutralization assays.
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The Translocation Motif of Hepatitis B Virus Envelope Proteins Is Dispensable for Infectivity
TL;DR: Two different mutated viruses containing a truncated TLM are used and showed their ability to infect human hepatocytes in primary culture, thus demonstrating the dispensability of the TLM for HBV infectivity.