Philipp Walch
European Bioinformatics Institute
12 Papers
42 Citations
Philipp Walch is an academic researcher from European Bioinformatics Institute. The author has contributed to research in topics: Salmonella enterica & Effector. The author has an hindex of 6, co-authored 12 publications. Previous affiliations of Philipp Walch include Heidelberg University & Massachusetts Institute of Technology.
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Papers
Bioprinted thrombosis-on-a-chip
Yu Shrike Zhang,Yu Shrike Zhang,Yu Shrike Zhang,Farideh Davoudi,Farideh Davoudi,Philipp Walch,Philipp Walch,Philipp Walch,Amir Manbachi,Amir Manbachi,Xuan Luo,Xuan Luo,Xuan Luo,Valeria Dell’Erba,Valeria Dell’Erba,Valeria Dell’Erba,Amir K. Miri,Amir K. Miri,Hassan Albadawi,Andrea Arneri,Andrea Arneri,Xiaoyun Li,Xiaoyun Li,Xiaoyun Li,Xiaoying Wang,Xiaoying Wang,Xiaoying Wang,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Mehmet R. Dokmeci,Ali Khademhosseini,Rahmi Oklu,Rahmi Oklu,Rahmi Oklu +33 more
TL;DR: In vitro 3D bioprinted blood coagulation models can be used to study the pathology of fibrosis, and particularly, in thrombosis, and this versatile platform may be conveniently extended to other vascularized fibrotic disease models.
Surface acoustic waves induced micropatterning of cells in gelatin methacryloyl (GelMA) hydrogels.
Shahid M Naseer,Amir Manbachi,Amir Manbachi,Amir Manbachi,Mohamadmahdi Samandari,Mohamadmahdi Samandari,Mohamadmahdi Samandari,Philipp Walch,Philipp Walch,Philipp Walch,Yuan Gao,Yuan Gao,Yu Shrike Zhang,Yu Shrike Zhang,Farideh Davoudi,Farideh Davoudi,Wesley Wang,Wesley Wang,Karen Abrinia,Jonathan M. Cooper,Ali Khademhosseini,Su Ryon Shin,Su Ryon Shin +22 more
TL;DR: The described acoustic force assembly method can be utilized not only to control the spatial distribution of the cells inside a 3D construct, but can also preserve the viability and functionality of the patterned cells (e.g. beating rates of cardiac cells).
Global mapping of Salmonella enterica-host protein-protein interactions during infection.
Philipp Walch,Joel Selkrig,Leigh A. Knodler,Mandy Rettel,Frank Stein,Keith C. Fernandez,Cristina Viéitez,Clement M. Potel,Karoline Scholzen,Matthias Geyer,Klemens Rottner,Olivia Steele-Mortimer,Mikhail M. Savitski,David W. Holden,Athanasios Typas +14 more
TL;DR: In this paper, a library of 32 Salmonella enterica serovar Typhimurium (STm) strains expressing chromosomally encoded affinity-tagged effectors and quantified effector-host PPIs in macrophages and epithelial cells.
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Starting a Medical Technology Venture as a Young Academic Innovator or Student Entrepreneur
Amir Manbachi,Katlin Kreamer-Tonin,Philipp Walch,Nao J. Gamo,Parastoo Khoshakhlagh,Yu Shrike Zhang,Yu Shrike Zhang,Charles Montague,Soumyadipta Acharya,Elizabeth A. Logsdon,Robert H. Allen,Nicholas J. Durr,Mark G. Luciano,Nicholas Theodore,Henry Brem,Youseph Yazdi +15 more
TL;DR: In this paper, the authors provide an overview of the existing landscape, the exciting rewards as well as risks awaiting a student entrepreneur, the challenges of the present ecosystem, and questions to consider prior to embarking on such a journey.
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SARS-CoV-2 infection remodels the host protein thermal stability landscape.
Joel Selkrig,Megan L. Stanifer,André Mateus,Karin Mitosch,Inigo Barrio-Hernandez,Mandy Rettel,Heeyoung Kim,Carlos G P Voogdt,Philipp Walch,Philipp Walch,Carmon Kee,Nils Kurzawa,Nils Kurzawa,Frank Stein,Clement M. Potel,Anna Jarzab,Bernhard Kuster,Ralf Bartenschlager,Ralf Bartenschlager,Steeve Boulant,Steeve Boulant,Pedro Beltrao,Athanasios Typas,Mikhail M. Savitski +23 more
TL;DR: This work discovered pronounced temporal alterations in host protein thermostability during infection, which converged on cellular processes including cell cycle, microtubule and regulation of RNA splicing and provides deeper resolution into the molecular changes induced by SARS-CoV-2 infection.