Peter Sebbel
Novartis
8 Papers
336 Citations
Peter Sebbel is an academic researcher from Novartis. The author has contributed to research in topics: Antigen & Epitope. The author has an hindex of 6, co-authored 8 publications.
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Papers
VSIG4, a B7 family-related protein, is a negative regulator of T cell activation.
Lorenz Vogt,Nicole Schmitz,Michael O. Kurrer,Monika Bauer,Heather I. Hinton,Silvia Behnke,Dominique Gatto,Peter Sebbel,Roger R. Beerli,Ivo Sonderegger,Manfred Kopf,Philippe Saudan,Martin F. Bachmann +12 more
TL;DR: The specific expression of VSIG4 on resting macrophages in tissue suggests that this inhibitory ligand may be important for the maintenance of T cell unresponsiveness in healthy tissues.
Patent
Molecular Antigen Array
Wolfgang A. Renner,Martin F. Bachmann,Alain Tissot,Patrick Maurer,Franziska Lechner,Peter Sebbel,Christine Piossek +6 more
- 21 Jan 2002
TL;DR: In this paper, a composition comprising an AP205 virus like particle (VLP) and an antigen is presented, which is useful in the production of compositions for inducing immune responses that are useful for the prevention or treatment of diseases, disorders or conditions including infectious diseases, allergies, cancer, drug addiction, poisoning and to efficiently induce self-specific immune responses, in particular antibody responses.
175
Virus-Like Particles as a Modular System for Novel Vaccines
Franziska Lechner,Andrea Jegerlehner,Alain Tissot,Patrik Maurer,Peter Sebbel,Wolfgang A. Renner,Gary T. Jennings,Martin F. Bachmann +7 more
TL;DR: This work presents a molecular assembly system that renders antigens of choice highly repetitive and efficient antibody responses may be induced in the absence of adjuvants resulting in protection from viral infection and allergic reactions.
98
Patent
Molecular antigen arrays and vaccines
Peter Sebbel,Nicolas Dunant,Martin F. Bachmann,Alain Tissot,Franziska Lechener +4 more
- 02 May 2001
TL;DR: In this article, a core particle is coated with any desired antigen in a highly ordered and repetitive fashion as the result of specific interactions, and the compositions of the invention are useful for the production of vaccines for the prevention of infectious diseases, treatment of allergies and the treatment of cancers.
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Patent
Molecular antigen array presenting amyloid beta
Patrick Maurer,Franziska Lechner,Rainer Ortmann,Rainer Martin Lueoend,Matthias Staufenbiel,Peter Frey,Wolfgang A. Renner,Martin F. Bachmann,Alain Tissot,Peter Sebbel,Christine Piossek +10 more
- 21 Jan 2002
TL;DR: In this article, an ordered and repetitive antigen or antigenic determinant array is used for the production of vaccines for the treatment of infectious diseases, the treatment for allergies and as a pharmaccine to prevent or cure cancer.
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