Péter Sántha
University of Szeged
53 Papers
214 Citations
Péter Sántha is an academic researcher from University of Szeged. The author has contributed to research in topics: TRPV1 & Capsaicin. The author has an hindex of 18, co-authored 48 publications. Previous affiliations of Péter Sántha include Imperial College London.
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Papers
The role of the vanilloid (capsaicin) receptor (TRPV1) in physiology and pathology.
TL;DR: The molecular, pharmacological and physiological characteristics, and putative functions, of the vanilloid receptor 1 are summarized, and the therapeutic potential of this molecule is discussed.
295
Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes.
Dorte Xenia Gram,Bo Ahrén,István Nagy,Uffe Bang Olsen,Christian L. Brand,Frank Sundler,René Tabanera,Ove Svendsen,Richard D. Carr,Péter Sántha,Péter Sántha,Nils Wierup,Anker Jon Hansen +12 more
TL;DR: It is proposed that the activity of islet‐innervating capsaicin‐sensitive fibers may have a role in the development of reduced insulin secretion in human type 2 diabetes mellitus.
159
Localization of the endocannabinoid-degrading enzyme fatty acid amide hydrolase in rat dorsal root ganglion cells and its regulation after peripheral nerve injury.
Isobel J. Lever,Michelle Robinson,Mario Cibelli,Cleoper C. Paule,Péter Sántha,Louis Yee,Stephen P. Hunt,Benjamin F. Cravatt,Maurice R. Elphick,István Nagy,Andrew S.C. Rice +10 more
TL;DR: The location of FAAH is revealed in neural tissue involved in peripheral nociceptive transmission in adult rat DRG, sciatic nerve, and spinal cord after chronic inflammation of the rat hindpaw 2 d after injection of complete Freund's adjuvant.
63
Insulin induces cobalt uptake in a subpopulation of rat cultured primary sensory neurons
Vivian Sathianathan,António Avelino,Ana Charrua,Péter Sántha,Klara Matesz,Francisco Cruz,István Nagy +6 more
TL;DR: The findings suggest that insulin activates a subpopulation of primary sensory neurons, probably through phosphorylation‐ and/or phosphatidylinositol(4,5)biphosphate hydrolysis‐evoked activation of the vanilloid receptor 1, which might play a role in the development of burning pain sensation in hyperinsulinism.
54
Functional and Histochemical Characterization of a Uterine Adrenergic Denervation Process in Pregnant Rats
TL;DR: Findings demonstrate a progressive, frequency-related reduction of nerve-mediated uterine contractions beginning in midterm pregnancy, in parallel with a gradual loss of adrenergic nerve fibers.