Peter Paul Heym
Leibniz Association
6 Papers
7 Citations
Peter Paul Heym is an academic researcher from Leibniz Association. The author has contributed to research in topics: PARP inhibitor & Osseointegration. The author has an hindex of 3, co-authored 4 publications.
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Papers
Virtual screening for plant PARP inhibitors – what can be learned from human PARP inhibitors?
Peter Paul Heym,Wolfgang Brandt,Ludger A. Wessjohann,Ludger A. Wessjohann,Hans-Joachim Niclas +4 more
TL;DR: A developed virtual screening route has been applied to screen a commercial database for AtPARP-1 inhibitors, and predictions of the applicability of that multi-step process on acommercial database have been explored.
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Influencing factors on the foot health of captive Asian elephants (Elephas maximus) in European zoos
Paulin Wendler,Nicolas Ertl,Michael Flügger,Endre Sós,Paul R. Torgerson,Peter Paul Heym,Christian Schiffmann,Marcus Clauss,Jean-Michel Hatt +8 more
TL;DR: Reduced foot health in Asian elephants in European zoos might be an indicator of a generally poorer husbandry system, and a holistic consideration appears more appropriate.
6
A yeast growth assay to characterize plant poly(ADP-ribose) polymerase (PARP) proteins and inhibitors.
TL;DR: An assay based on heterologous expression of PARP genes from the model plant Arabidopsis thaliana in yeast provides a fast and simple means to identify target proteins and pharmacological inhibitors of AtPARP1.
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AI-Powered Virtual Screening of Large Compound Libraries Leads to the Discovery of Novel Inhibitors of Sirtuin-1.
Anastasiia Gryniukova,Florian Kaiser,Iryna Myziuk,Diana O. Alieksieieva,Christoph Leberecht,Peter Paul Heym,Olga O Tarkhanova,Yurii S. Moroz,Petro Borysko,V. Joachim Haupt +9 more
TL;DR: This work shows how smart algorithms reduce large screening collections to target-specific sets of just a few hundred small molecules, allowing for a much faster and more cost-effective hit discovery process.
Loading characteristics data applied on osseointegrated implant by transfemoral bone-anchored prostheses fitted with state-of-the-art components during daily activities
TL;DR: In this article , Frossard et al. presented the overall and individual loading characteristics applied on transfemoral press-fit osseointegrated implant generated by bone-anchored prostheses fitted with state-of-the-art components during daily activities.