Peter P. C. Tan
Memorial Hospital of South Bend
36 Papers
410 Citations
Peter P. C. Tan is an academic researcher from Memorial Hospital of South Bend. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 18, co-authored 36 publications.
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Papers
Concentration and regional distribution of propofol in brain and spinal cord during propofol anesthesia in the rat.
TL;DR: High brain/blood and brain/plasma ratios during anesthesia in Sprague-Dawley rats suggest that propofol manifests a pharmacokinetic profile that is different from at least thiopental.
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Video-Assisted Cardiac Surgery in Closure of Atrial Septal Defect
Chang Chau-Hsiung,Pyng Jing Lin,Jaw-Ji Chu,Hui-Ping Liu,Feng-Chun Tsai,Fun-Chung Lin,Cheng-Wen Chiang,Wen-Jen Su,Min-Wen Yang,Peter P. C. Tan +9 more
TL;DR: The experience demonstrates that video-assisted cardiac surgery is technically feasible and can be used with excellent results for the repair of congenital heart defects in general.
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Epidural dexamethasone reduces the incidence of backache after lumbar epidural anesthesia.
TL;DR: In this study, there was a significant association between postepidural backache and multiple attempts at epidural needle insertion and epidural dexamethasone reduced the incidence and severity of postepic backache.
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Protection of the brain by retrograde cerebral perfusion during circulatory arrest.
Pyng Jing Lin,Chau-Hsiung Chang,Peter P. C. Tan,Chun-Chieh Wang,Jen-Ping Chang,Dah-Wel Liu,Jaw-Ji Chu,Kuei-Ton Tsai,Chiung-Lun Kao,Ming-Jang Hsieh +9 more
TL;DR: Retrograde cerebral perfusion can effectively protect the brain from ischemic injury and extend the safe period of hypothermic circulatory arrest and with the aid of prolonged circulatory Arrest can probably be performed safely with moderate hypothermia.
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Modulations of spinal serotonin activity affect the development of morphine tolerance.
Jihn-Yih Li,C.-H. Wong,Eagle Yi-Kung Huang,Yen-Chien Lin,Yun-Long Chen,Peter P. C. Tan,Jin-Chung Chen +6 more
TL;DR: Activity of spinal 5-HT-containing neurons plays a crucial role during the development of morphine tolerance, and the binding study indicated that the affinity of lumbar &mgr;-opioid receptors decreased 196% in 5- HT-depleted rats, whereas there was no effect on apparent binding.
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