Peter Lukacs
Technical University of Košice
53 Papers
89 Citations
Peter Lukacs is an academic researcher from Technical University of Košice. The author has contributed to research in topics: Sodium channel & Gating. The author has an hindex of 11, co-authored 50 publications. Previous affiliations of Peter Lukacs include Hungarian Academy of Sciences & Eötvös Loránd University.
Chat about Author
Papers
Voltage-Gated Ion Channel Dysfunction Precedes Cardiomyopathy Development in the Dystrophic Heart
Xaver Koenig,Sandra Dysek,Stefanie Kimbacher,Agnes K. Mike,René Cervenka,Peter Lukacs,Katrin Nagl,Xuan B. Dang,Hannes Todt,Reginald E. Bittner,Karlheinz Hilber +10 more
TL;DR: Ion channel impairments precede pathology development in the dystrophic heart, and may thus be considered potential cardiomyopathy triggers.
Surface analysis of polymeric substrates used for inkjet printing technology
Alena Pietrikova,Peter Lukacs,Dagmar Jakubéczyová,Beáta Ballóková,Jerzy Potencki,Grzegorz Tomaszewski,Jan Pekárek,Katerina Prikrylova,Martin Fides +8 more
TL;DR: In this paper, the impact of applied chemical agents for surface treatment onto the wettability is analyzed for polyimide, polyethylene terephthalate and polyethylenes naphthalene substrates.
63
The Enigmatic Drug Binding Site for Sodium Channel Inhibitors
Arpad Mike,Peter Lukacs +1 more
TL;DR: It is concluded that sodium channel inhibitors must be heterogenous in terms of binding sites and inhibition mechanisms, and it is proposed that this heterogeneity should be taken into consideration during drug development.
40
Non-blocking modulation contributes to sodium channel inhibition by a covalently attached photoreactive riluzole analog.
Peter Lukacs,Peter Lukacs,Mátyás C. Földi,Luca Valanszki,Emilio Casanova,Beáta Biri-Kovács,László Nyitray,András Málnási-Csizmadia,Arpad Mike,Arpad Mike +9 more
TL;DR: The finding that non- blocking modulation is possible, may open a novel avenue for drug development because non-blocking modulators could be more specific in treating hyperactivity-linked diseases.
A Molecular Switch between the Outer and the Inner Vestibules of the Voltage-gated Na+ Channel
Touran Zarrabi,René Cervenka,Walter Sandtner,Peter Lukacs,Xaver Koenig,Karlheinz Hilber,Markus Mille,Gregory M. Lipkind,Harry A. Fozzard,Hannes Todt +9 more
TL;DR: It is reported that amino acid Ile-1575 in the middle of transmembrane segment 6 of domain IV (DIV-S6) in the adult rat skeletal muscle isoform of the voltage-gated sodium channel (rNaV1.4) may act as molecular switch allowing for interaction between outer and inner vestibules.
22