Peter Kraft
Ludwig Maximilian University of Munich
5 Papers
3 Citations
Peter Kraft is an academic researcher from Ludwig Maximilian University of Munich. The author has contributed to research in topics: GPVI & Platelet. The author has an hindex of 2, co-authored 5 publications.
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Papers
The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction
Judith M.M. van Eeuwijk,David Stegner,David J. Lamb,Peter Kraft,Sarah E. Beck,Ina Thielmann,Friedemann Kiefer,Barbara Walzog,Guido Stoll,Bernhard Nieswandt +9 more
TL;DR: Mice lacking Syk in platelets specifically are protected from arterial thrombus formation and ischemic stroke but display unaltered hemostasis, providing direct evidence that pharmacological Syk inhibition might provide a safe therapeutic strategy to prevent arterialThrombosis and to limit infarct progression in acute stroke.
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TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice.
Sanjeev K. Gotru,Wenchun Chen,Peter Kraft,Isabelle C. Becker,Karen Wolf,Simon Stritt,Susanna Zierler,Heike M. Hermanns,Deviyani Rao,Anne-Laure Perraud,Carsten Schmitz,René P. Zahedi,Peter J. Noy,Michael G. Tomlinson,Thomas Dandekar,Masayuki Matsushita,Vladimir Chubanov,Thomas Gudermann,Guido Stoll,Bernhard Nieswandt,Attila Braun +20 more
TL;DR: The results identify TRPM7 kinase as a key modulator of phospholipase C signaling and store-operated Ca2+ entry in platelets and the protection of Trpm7R/R mice from acute ischemic disease without developing intracranial hemorrhage indicates that TRPM 7 kinase might be a promising antithrombotic target.
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mice by inducing dysfunction of the cerebral microvasculature Regulatory T cells are strong promoters of acute ischemic stroke in
H. Wiendl,Sven G. Meuth,Yoichiro Iwakura,Alma Zernecke,Tim Sparwasser,Bernhard Nieswandt,Marc Brede,Csanad Varallyay,Mirko Pham,M. Bendszus,Peter M. Jakob,Tim Magnus,Friederike Langhauser,Xavier Helluy,Tobias Schwarz,Stefan Bittner,Christoph Kleinschnitz,Peter Kraft,Angela Dreykluft,Ina Hagedorn,Kerstin Göbel +20 more
- 01 Jan 2013
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Diagnostik und Akuttherapie des ischämischen Schlaganfalls
Peter Kraft,Sami Nasri,Mirjam Dreikorn,Martin Köhrmann,Christoph Kleinschnitz +4 more
- 01 Dec 2019
TL;DR: Der zunehmende Einsatz der mechanischen Thrombektomie wirft die Frage einer prähospitalen Triagierung von Patienten mit IS auf, ist allerdings bei Kontraindikationen nicht immer einsetzbar.
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