Peter Jeffery
GlaxoSmithKline
10 Papers
155 Citations
Peter Jeffery is an academic researcher from GlaxoSmithKline. The author has contributed to research in topics: Dentifrice & Toothpaste. The author has an hindex of 7, co-authored 10 publications.
Chat about Author
Papers
An in situ study investigating dentine tubule occlusion of dentifrices following acid challenge
Ryan C. Olley,Peter Pilecki,Nathan Hughes,Peter Jeffery,Rupert Austin,Rebecca Moazzez,David Bartlett +6 more
TL;DR: This 4-day in situ study investigated the properties of commercially available dentifrices designed to occlude dentine tubules and their resistance to an agitated acid challenge, finding the arginine-based dentifrice is more susceptible to acid challenge.
85
•Journal Article
A comparative clinical study investigating the efficacy of a test dentifrice containing 8% strontium acetate and 1040 ppm sodium fluoride versus a marketed control dentifrice containing 8% arginine, calcium carbonate, and 1450 ppm sodium monofluorophosphate in reducing dentinal hypersensitivity.
Nathan Hughes,Stephen Mason,Peter Jeffery,Helen Welton,Maira Tobin,Caoimhe O'Shea,Mairead Browne +6 more
TL;DR: The 8% strontium acetate, 1040 ppm sodium fluoride dentifrice provided significant reductions in dentin hypersensitivity after two, four, and eight weeks of product use.
59
•Journal Article
Randomized in situ clinical study comparing the ability of two new desensitizing toothpaste technologies to occlude patent dentin tubules.
Nicola X West,Emma L Macdonald,Sian B Jones,Nicholas C A Claydon,Nathan Hughes,Peter Jeffery +5 more
TL;DR: Application of the 5% NovaMin toothpaste to dentin showed better dentin tubule occlusion and retention abilities in an oral environment under dietary acid challenge conditions, more so than the 8% arginine toothpaste technology.
52
•Journal Article
Confirmation of efficacy in providing relief from the pain of dentin hypersensitivity of an anhydrous dentifrice containing 0.454% with or without stannous fluoride in an 8-week randomized clinical trial.
TL;DR: A randomized, examiner-blind, parallel, two treatment group, stratified (by maximum baseline Schiff sensitivity score), 8-week clinical study carried out in 119 healthy subjects with at least two sensitive teeth, who met all study criteria at the screening and baseline visits.
27
•Journal Article
The efficacy of an experimental dentifrice containing 0.454% w/w stannous fluoride in providing relief from the pain of dentin hypersensitivity: an 8-week clinical study.
Charles R. Parkinson,Nathan Hughes,Peter Jeffery,Ritika Jain,Liam Kennedy,Qaqish J,John Gallob,Stephen Mason +7 more
TL;DR: Between treatment analyses demonstrated the test dentifrice to be significantly better at relieving subjects' sensitivity, for both validated clinical measures, compared to the negative control.
22