Peter James
ETH Zurich
25 Papers
844 Citations
Peter James is an academic researcher from ETH Zurich. The author has contributed to research in topics: Peptide sequence & Calmodulin. The author has an hindex of 18, co-authored 25 publications. Previous affiliations of Peter James include University of Padua.
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Papers
Protein identification in the post-genome era: the rapid rise of proteomics
TL;DR: The recent explosion in sequence information in the databases arose from the pioneering work on separation methods by Frederick Sanger which paved the way for the development of protein and DNA/RNA sequencing and culminated in the receipt of two Nobel prizes by Sanger.
Proteomics and automation
Manfredo Quadroni,Peter James +1 more
TL;DR: In this review, the weak points in the chain of analysis are highlighted and recent trends toward automation in instrumentation and software are summarized and the author's own personal view of future developments in the field is offered.
217
Hydrophobic binding of the ectodomain of influenza hemagglutinin to membranes occurs through the "fusion peptide".
TL;DR: It is demonstrated that the hydrophobic interaction is mediated solely by the so-called "fusion peptide" which corresponds to the NH2-terminal segment of the BHA2 subunit of nature influenza hemagglutinin.
213
Peptide sequence analysis and molecular cloning reveal two calcium pump isoforms in the human erythrocyte membrane.
Emanuel E. Strehler,Peter James,R Fischer,Roger Heim,Thomas Vorherr,A G Filoteo,J T Penniston,Ernesto Carafoli +7 more
TL;DR: The two erythrocyte Ca2+ pumps display high sequence divergence in a few localized regions that may determine isoform-specific functional specializations; for example, the putative extracellular loop separating transmembrane domains 1 and 2, the highly negatively charged region previously suggested to be involved in Ca2- binding, and the site of cAMP-dependent protein kinase phosphorylation.
167
Interaction of calmodulin with the calmodulin binding domain of the plasma membrane Ca2+ pump.
Thomas Vorherr,Peter James,Joachim Krebs,Ágnes Enyedi,Ágnes Enyedi,Daniel J. McCormick,John T. Penniston,Ernesto Carafoli +7 more
TL;DR: Circular dichroism experiments have shown that it interacted with the calmodulin binding domain, supporting the suggestion that the latter, or a portion of it, may act as a natural inhibitor of the pump.
138