Peter J. Noy
University of Birmingham
30 Papers
39 Citations
Peter J. Noy is an academic researcher from University of Birmingham. The author has contributed to research in topics: Tetraspanin & ADAM10. The author has an hindex of 16, co-authored 30 publications. Previous affiliations of Peter J. Noy include University of Bristol.
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Papers
The Transcription Factor Encyclopedia
Dimas Yusuf,Stefanie L. Butland,Magdalena I. Swanson,Eugene Bolotin,Amy Ticoll,Warren A. Cheung,Xiao Yu Cindy Zhang,Christopher Td Dickman,Debra L. Fulton,Jonathan Lim,Jake Schnabl,Oscar H. P. Ramos,Mireille Vasseur-Cognet,Charles N. de Leeuw,Elizabeth M. Simpson,Gerhart U. Ryffel,Eric Lam,Ralf Kist,Miranda Sc Wilson,Raquel Marco-Ferreres,Jan J. Brosens,Leonardo Beccari,Paola Bovolenta,Bérénice A. Benayoun,Lara J. Monteiro,Helma Dc Schwenen,Lars Grøntved,Elizabeth D. Wederell,Susanne Mandrup,Reiner A. Veitia,Harini Chakravarthy,Pamela A. Hoodless,M. Michela Mancarelli,Bruce E. Torbett,Alison H. Banham,Sekhar P. Reddy,Rebecca L. Cullum,Michaela Liedtke,Mario P. Tschan,Michelle Vaz,Angie Rizzino,Mariastella Zannini,Seth Frietze,Peggy J. Farnham,Astrid Eijkelenboom,Philip J. Brown,David Laperrière,Dominique Leprince,Tiziana de Cristofaro,Kelly L. Prince,Marrit Putker,Luis del Peso,Gieri Camenisch,Roland H. Wenger,Michal Mikula,Marieke Rozendaal,Sylvie Mader,Jerzy Ostrowski,Simon J. Rhodes,Capucine Van Rechem,Gaylor Boulay,Sam W. Z. Olechnowicz,Mary B. Breslin,Michael S. Lan,Kyster K. Nanan,Michael Wegner,Juan Hou,Rachel D. Mullen,Stephanie C. Colvin,Peter J. Noy,Carol F. Webb,Matthew E. Witek,Scott Ferrell,Juliet M. Daniel,Jason Y. Park,Scott A. Waldman,Daniel J. Peet,Michael J. Taggart,Padma-Sheela Jayaraman,Julien J. Karrich,Bianca Blom,Farhad Vesuna,Henriette O'Geen,Yunfu Sun,Richard M. Gronostajski,Mark W. Woodcroft,Margaret R. Hough,Edwin Chen,Nicholas Europe-Finner,Magdalena Karolczak-Bayatti,Jarrod Bailey,Oliver Hankinson,Venu Raman,David P. LeBrun,Shyam Biswal,Christopher J. Harvey,Jason P. DeBruyne,John B. Hogenesch,Robert F. Hevner,Christophe Héligon,Xin M. Luo,Marissa Cathleen Blank,Kathleen J. Millen,David S. Sharlin,Douglas Forrest,Karin Dahlman-Wright,Chunyan Zhao,Yuriko Mishima,Satrajit Sinha,Rumela Chakrabarti,Elodie Portales-Casamar,Frances M. Sladek,Philip Bradley,Wyeth W. Wasserman +113 more
TL;DR: The Transcription Factor Encyclopedia (TFe), a new web-based compendium of mini review articles on transcription factors (TFs) that is founded on the principles of open access and collaboration, is presented.
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TspanC8 Tetraspanins and A Disintegrin and Metalloprotease 10 (ADAM10) Interact via Their Extracellular Regions: EVIDENCE FOR DISTINCT BINDING MECHANISMS FOR DIFFERENT TspanC8 PROTEINS.
Peter J. Noy,Jing Yang,Jasmeet S. Reyat,Alexandra L. Matthews,Alice E. Charlton,Joanna Furmston,David A. Rogers,G. Ed Rainger,Michael G. Tomlinson +8 more
TL;DR: It is suggested that ADAM10 may adopt distinct conformations in complex with different TspanC8s, which could impact on substrate selectivity and is identified for potential interaction-disrupting therapeutic targeting.
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Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins.
TL;DR: Therapeutic targetting of specific TspanC8/ADAM10 complexes could allow ADAM10 targetting in a cell type- or substrate-specific manner, to treat certain diseases while minimising toxicity.
RhoJ interacts with the GIT–PIX complex and regulates focal adhesion disassembly
Eleanor Wilson,Katarzyna B. Leszczynska,Natalie S. Poulter,Francesca Edelmann,Victoria A. Salisbury,Peter J. Noy,Andrea Bacon,Joshua Z. Rappoport,John K. Heath,Roy Bicknell,Victoria L. Heath +10 more
TL;DR: RhoJ-knockout mice showed reduced tumour growth and diminished tumour vessel density, identifying a role for RhoJ in mediating tumour angiogenesis and giving new insight into the molecular function of RhoGTPase in regulating cell motility and tumours vessel formation.
TRPM7 Kinase Controls Calcium Responses in Arterial Thrombosis and Stroke in Mice.
Sanjeev K. Gotru,Wenchun Chen,Peter Kraft,Isabelle C. Becker,Karen Wolf,Simon Stritt,Susanna Zierler,Heike M. Hermanns,Deviyani Rao,Anne-Laure Perraud,Carsten Schmitz,René P. Zahedi,Peter J. Noy,Michael G. Tomlinson,Thomas Dandekar,Masayuki Matsushita,Vladimir Chubanov,Thomas Gudermann,Guido Stoll,Bernhard Nieswandt,Attila Braun +20 more
TL;DR: The results identify TRPM7 kinase as a key modulator of phospholipase C signaling and store-operated Ca2+ entry in platelets and the protection of Trpm7R/R mice from acute ischemic disease without developing intracranial hemorrhage indicates that TRPM 7 kinase might be a promising antithrombotic target.
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