Peter Haviernik
Case Western Reserve University
12 Papers
72 Citations
Peter Haviernik is an academic researcher from Case Western Reserve University. The author has contributed to research in topics: Haematopoiesis & Hematopoietic stem cell. The author has an hindex of 8, co-authored 12 publications. Previous affiliations of Peter Haviernik include American Red Cross.
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Papers
MicroRNA 184 regulates expression of NFAT1 in umbilical cord blood CD4 + T-cells
R. Patrick Weitzel,Mathew Lesniewski,Peter Haviernik,Suzanne Kadereit,Patrick Leahy,Nicholas J. Greco,Nicholas J. Greco,Mary J. Laughlin +7 more
TL;DR: Evidence is provided that a specific microRNA, miR-184, inhibits NFAT1 protein expression elicited by UCB CD4+ T cells and a novel function for microRNA in the early adaptive immune response is revealed.
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Cited2 is required for normal hematopoiesis in the murine fetal liver.
TL;DR: The present study uncovers for the first time a novel role of Cited2 in the maintenance of hematopoietic homeostasis during embryogenesis and thus provides new insights into the molecular regulation ofhematopOietic development.
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Bone marrow transplantation combined with gene therapy to induce antigen-specific tolerance and ameliorate EAE.
TL;DR: The results suggest that HSC may be useful to achieve long-lasting tolerance to protect mice from EAE and possibly to promote CNS repair in ongoing EAE.
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Safety concerns related to hematopoietic stem cell gene transfer using retroviral vectors.
Peter Haviernik,Kevin D. Bunting +1 more
TL;DR: In the field of gene therapy, retroviral vector design and safety testing are at the forefront of the field as discussed by the authors, with the goal of gene transfer into hematopoietic stem cells (HSCs).
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Tissue inhibitor of matrix metalloproteinase-1 overexpression in M1 myeloblasts impairs IL-6-induced differentiation
Peter Haviernik,Carisa Lahoda,Carisa Lahoda,Heath L. Bradley,Teresa S. Hawley,Ali Ramezani,Robert G. Hawley,Robert G. Hawley,Maryalice Stetler-Stevenson,William G. Stetler-Stevenson,Kevin D. Bunting,Kevin D. Bunting +11 more
TL;DR: It is demonstrated that TIMP-1 overexpression impairs differentiation of the myeloblastic M1 cell line following interleukin (IL)-6 stimulation, indicating that functional effects on growth and differentiation of M1 cells were primarily through an autocrine mechanism.
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