Peter C. Phillips
Children's Hospital of Philadelphia
86 Papers
1.4K Citations
Peter C. Phillips is an academic researcher from Children's Hospital of Philadelphia. The author has contributed to research in topics: Medulloblastoma & Medicine. The author has an hindex of 40, co-authored 85 publications. Previous affiliations of Peter C. Phillips include Memorial Sloan Kettering Cancer Center & Hospital of the University of Pennsylvania.
Chat about Author
Papers
The Genetic Landscape of the Childhood Cancer Medulloblastoma
D. Williams Parsons,D. Williams Parsons,Meng Li,Xiaosong Zhang,Siân Jones,Rebecca J. Leary,Jimmy Lin,Simina M. Boca,Hannah Carter,Josue Samayoa,Chetan Bettegowda,Chetan Bettegowda,Gary L. Gallia,George I. Jallo,Zev A. Binder,Yuri Nikolsky,James Hartigan,Doug R. Smith,Daniela S. Gerhard,Daniel W. Fults,Scott R. VandenBerg,Mitchel S. Berger,Suely Kazue Nagahashi Marie,Sueli Mieko Oba Shinjo,Carlos Clara,Peter C. Phillips,Jane E. Minturn,Jaclyn A. Biegel,Alexander R. Judkins,Adam C. Resnick,Phillip B. Storm,Tom Curran,Yiping He,B.K. Ahmed Rasheed,Henry S. Friedman,Stephen T. Keir,Roger E. McLendon,Paul A. Northcott,Michael D. Taylor,Peter C. Burger,Gregory J. Riggins,Gregory J. Riggins,Rachel Karchin,Giovanni Parmigiani,Darell D. Bigner,Hai Yan,Nick Papadopoulos,Bert Vogelstein,Kenneth W. Kinzler,Victor E. Velculescu +49 more
TL;DR: Key differences between the genetic landscapes of adult and childhood cancers are demonstrated, dysregulation of developmental pathways as an important mechanism underlying MBs is highlighted, and a role for a specific type of histone methylation in human tumorigenesis is identified.
Surgery with or without radiation therapy in the management of craniopharyngiomas in children and young adults
Diana Stripp,Amit Maity,Anna J. Janss,Jean B. Belasco,Zelig Tochner,Joel W. Goldwein,Thomas Moshang,Lucy B. Rorke,Peter C. Phillips,Leslie N. Sutton,Hui-Kuo G. Shu +10 more
TL;DR: RT given either immediately after STR or at relapse is effective in controlling craniopharyngiomas, and a single institution's experience with such patients is reported.
269
Prognostic signs in the surgical management of plexiform neurofibroma: The Children’s Hospital of Philadelphia experience, 1974-1994
Michael N. Needle,Avital Cnaan,James J. Dattilo,Jane Chatten,Peter C. Phillips,Stephen Shochat,Leslie N. Sutton,Sheila N. Vaughan,Elaine H. Zackai,Huaqing Zhao,Patricia T. Molloy +10 more
TL;DR: Tumor progression is a serious problem for children with plexiform neurofibroma and younger children, children with tumors of the head/neck/face, and tumors that cannot be nearly completely removed are at particular risk.
247
Late cognitive and radiographic changes related to radiotherapy Initial prospective findings
Carol L. Armstrong,Jill V. Hunter,G. E. Ledakis,B. Cohen,E. M. Tallent,B Goldstein,Zelig Tochner,Robert H. Lustig,K. D. Judy,A A Pruitt,J. E. Mollman,E. M. Stanczak,M. Y. Jo,T. L. Than,Peter C. Phillips +14 more
TL;DR: There was no evidence of a general cognitive decline or progression of white matter changes after 3 years of XRT at this frequently used dose and volume in the absence of other clinical risk factors.
212
•Journal Article
MYC messenger RNA expression predicts survival outcome in childhood primitive neuroectodermal tumor/medulloblastoma.
Michael A. Grotzer,Michael D. Hogarty,Anna J. Janss,Xueyuan Liu,Huaquing Zhao,Angelika Eggert,Leslie N. Sutton,Lucy B. Rorke,Garrett M. Brodeur,Peter C. Phillips +9 more
TL;DR: Low MYC mRNA expression is a powerful independent predictor of favorable clinical outcome in PNET/MB and may be incorporated in prospective P NET/MB clinical trials to aid in treatment planning.
182