Peter A. Minchella
Cornell University
10 Papers
22 Citations
Peter A. Minchella is an academic researcher from Cornell University. The author has contributed to research in topics: Medicine & Hepcidin. The author has an hindex of 4, co-authored 4 publications.
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Papers
Complex Anemia in Tuberculosis: The Need to Consider Causes and Timing When Designing Interventions
TL;DR: Iron-based interventions are needed for IDA and IDA+AI, and monitoring of iron biomarkers reveals a window for intervention opening as early as 2 months into tuberculosis treatment, which is associated with significant reductions in AI.
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Elevated Hepcidin Is Part of a Complex Relation That Links Mortality with Iron Homeostasis and Anemia in Men and Women with HIV Infection
Peter A. Minchella,Andrew E. Armitage,Bakary Darboe,Momodou W. Jallow,Hal Drakesmith,Assan Jaye,Andrew M. Prentice,Joann M. McDermid +7 more
TL;DR: Elevated hepcidin is independently associated with greater mortality in men and women with HIV infection, and hepcIDin is also part of a complex relation linking iron homeostasis, anemia, and HIV.
Elevated hepcidin at HIV diagnosis is associated with incident tuberculosis in a retrospective cohort study.
Peter A. Minchella,Andrew E. Armitage,Bakary Darboe,Momodou W. Jallow,Hal Drakesmith,Assan Jaye,Andrew M. Prentice,Joann M. McDermid +7 more
TL;DR: Greater hepcidin was associated with significantly increased likelihood of TB after a median time to TB of 6 months, and elucidation of iron-related causal mechanisms and time-sensitive biomarkers that identify individual changes in TB risk are needed.
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Iron homeostasis and progression to pulmonary tuberculosis disease among household contacts
TL;DR: Investigation of iron homeostasis biomarkers as risk factors for progression to TB in household contacts in The Gambia found low transferrin around the time of known exposure to infectious TB was a disease progression risk factor among all TB-progressors.
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Comparison of HIV prevalence, incidence, and viral load suppression in Zambia population-based HIV impact assessments from 2016 and 2021.
Lloyd Mulenga,Jonas Z Hines,Kristen A Stafford,Kumbutso Dzekedzeke,Suilanji Sivile,Brianna Lindsay,Mumbi Chola,Faith Ussery,Hetal Patel,Alash'le Abimiku,Sehin Birhanu,Peter A. Minchella,Thomas Stevens,Brave Hanunka,Tina Chisenga,Aaron Shibemba,Sombo Fwoloshi,Mwiche N. S. Siame,John Mutukwa,Lameck Chirwa,Mpanji Siwingwa,Georgina Mulundu,Chinedu William Agbakwuru,Prichard T. Mapondera,Mervi Detorio,Simon Agolory,Mwaka Monze,Megan A. Bronson,Man E. Charurat +28 more
TL;DR: HIV prevalence and viral load suppression (VLS) in Zambia have decreased between 2016 and 2021, but there are still challenges to achieving epidemic control.
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