Peng T. Khaw
UCL Institute of Ophthalmology
407 Papers
2.4K Citations
Peng T. Khaw is an academic researcher from UCL Institute of Ophthalmology. The author has contributed to research in topics: Glaucoma & Medicine. The author has an hindex of 76, co-authored 394 publications. Previous affiliations of Peng T. Khaw include University of London & University College London.
Chat about Author
Papers
Prolonged antiscarring effects of ilomastat and MMC after experimental glaucoma filtration surgery.
TL;DR: Ilomastat successfully prolongs bleb survival and MMP inhibition may provide an additional, potentially safer method of controlling intraocular pressure, thus preventing failure of glaucoma surgery, and may also act as a potential adjuvant treatment when MMC alone is inadequate.
•Book Chapter
Principles of pharmacology in the eye.
Sahar Awwad,Sahar Awwad,Abeer Mohamed Ahmed,Abeer Mohamed Ahmed,Garima Sharma,Garima Sharma,Jacob S Heng,Peng T. Khaw,Steve Brocchini,Steve Brocchini,Alastair Lockwood +10 more
- 01 Dec 2017
TL;DR: Drug delivery to the posterior segment is a greater challenge and, currently, the standard route is via intravitreal injection, notwithstanding the risks of endophthalmitis and retinal detachment with frequent injections.
Comparative thermodynamic analysis in solution of a next generation antibody mimetic to VEGF
TL;DR: While the FpFs displayed similar thermodynamics and binding affinity to the full IgG, their enhanced protein stability, slower dissociation rate and lack of Fc effector functions could make FpF a potential next-generation therapy for local tissue-targeted indications.
Rac1 inhibition prevents tissue contraction and MMP mediated matrix remodeling in the conjunctiva.
TL;DR: Rac1 inhibition efficiently prevents conjunctival tissue and collagen matrix contraction and prevents matrix degradation.
SOX2 is required for adult human muller stem cell survival and maintenance of progenicity in vitro.
TL;DR: In vitro results parallel that seen when Sox2 is silenced in neural stem cells of lower species during development, and they suggest that Sox2 may have an important role in adult hMSC differentiation into retinal neurons in vitro.