Peihao Yin
Shanghai University
68 Papers
200 Citations
Peihao Yin is an academic researcher from Shanghai University. The author has contributed to research in topics: Medicine & Bufalin. The author has an hindex of 23, co-authored 60 publications. Previous affiliations of Peihao Yin include Anhui Medical University.
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Papers
Hypoxia Induces Drug Resistance in Colorectal Cancer through the HIF-1α/miR-338-5p/IL-6 Feedback Loop
Ke Xu,Ke Xu,Yueping Zhan,Zeting Yuan,Yanyan Qiu,Haijing Wang,Guohua Fan,Jie Wang,Wei Li,Yijun Cao,Xian Shen,Jun Zhang,Xin Liang,Peihao Yin,Peihao Yin +14 more
TL;DR: An HIF-1α/miR-338-5p/IL-6 feedback circuit that is critical in hypoxia-mediated drug resistance in CRC is uncovered; targeting each member of this feedback loop could potentially reverse hypoxIA-induced drug resistanceIn CRC.
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MFN2 suppresses cancer progression through inhibition of mTORC2/Akt signaling.
Ke Xu,Guo Chen,Xiaobo Li,Xiaoqin Wu,Zhijie Chang,Jianhua Xu,Yu Zhu,Peihao Yin,Xin Liang,Lei Dong,Lei Dong +10 more
TL;DR: This study provides novel insights into the tumor progression associated with MFN2 deficiency and suggests that the importance of mTORC2 inhibitor in the treatment ofMFN2 downregulated cancer patients is suggested.
Cinobufacini Inhibits Colon Cancer Invasion and Metastasis via Suppressing Wnt/β-Catenin Signaling Pathway and EMT
Jie Wang,Han Cai,Qiaoli Liu,Yue Xia,Likai Xing,Qing-Song Zuo,Yong Zhang,Cao Chen,Ke Xu,Peihao Yin,Peihao Yin,Teng Chen,Teng Chen +12 more
TL;DR: The data proves that Cinobufacini can inhibit colon cancer invasion and metastasis both in vitro and in vivo; the mechanism is related by suppressing the Wnt/β-catenin signaling pathway and then inhibiting the EMT of CRC.
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Bufalin-loaded mPEG-PLGA-PLL-cRGD nanoparticles: preparation, cellular uptake, tissue distribution, and anticancer activity
Peihao Yin,Yan Wang,Yanyan Qiu,Hou Lili,Liu Xuan,Jian-min Qin,Yourong Duan,Peifeng Liu,Ming Qiu,Qi Li +9 more
TL;DR: BNPs had even size distribution, were stable, and had a slow-releasing and tumor-targeting effect, and significantly inhibited colon cancer growth in vitro and in vivo.
Photodynamic therapy synergizes with PD-L1 checkpoint blockade for immunotherapy of CRC by multifunctional nanoparticles.
Zeting Yuan,Guohua Fan,Honglei Wu,Chaolian Liu,Chaolian Liu,Yueping Zhan,Yanyan Qiu,Chenting Shou,Feng Gao,Jun Zhang,Peihao Yin,Ke Xu +11 more
TL;DR: Wang et al. as discussed by the authors reported the use of multifunctional nanoparticles (NPs) loaded with photosensitized mTHPC (mTHPC@VeC/T-RGD NPs)-mediated PDT treatment to potentiate the anti-tumor efficacy of PD-L1 blockade for colorectal cancer treatment and investigated the underlying mechanisms of photodynamic therapy (PDT) could effectively enhance checkpoint inhibitor therapeutic effect in this combination therapy.
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