Pei-Chen Chen
National Health Research Institutes
23 Papers
424 Citations
Pei-Chen Chen is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Antibiotic resistance & Medicine. The author has an hindex of 17, co-authored 20 publications. Previous affiliations of Pei-Chen Chen include National Institutes of Health.
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Papers
Emergence of reduced susceptibility and resistance to fluoroquinolones in Escherichia coli in Taiwan and contributions of distinct selective pressures.
L C McDonald,Feng-Jui Chen,Hsiu-Jung Lo,Hsiao-Chuan Yin,Po-Liang Lu,C H Huang,Pei-Chen Chen,Tsai Ling Lauderdale,Monto Ho +8 more
TL;DR: Whereas acute and chronic quinolone use in cancer patients is a major selective pressure for resistance, other undetermined but distinct selective pressures appear to be more responsible for reduced susceptibility to fluoroquinolones in E. coli.
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Emergence of extensively drug-resistant Acinetobacter baumannii complex over 10 years: Nationwide data from the Taiwan Surveillance of Antimicrobial Resistance (TSAR) program
Shu-Chen Kuo,Shu-Chen Kuo,Shu-Chen Kuo,Shan-Chwen Chang,Hui-Ying Wang,Jui-Fen Lai,Pei-Chen Chen,Yih-Ru Shiau,I-Wen Huang,Tsai-Ling Lauderdale +9 more
TL;DR: Although the prevalence of IRABC increased in all four regions of Taiwan over the years, central Taiwan had higher prevalence of XDRABC starting in 2008, and Multivariate analysis revealed that recovery from elderly patients, origins other than blood, from ICU settings, or geographic regions are independent factors associated with IRABC and XDRA BC.
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Multidrug resistance among different serotypes of clinical Salmonella isolates in Taiwan
Tsai-Ling Lauderdale,Frank Møller Aarestrup,Pei-Chen Chen,Jui-Fen Lai,Hui-Ying Wang,Yih-Ru Shiau,I-Wen Huang,Che Lun Hung +7 more
TL;DR: Resistance to ampicillin, chloramphenicol, streptomycin, sulfamethoxazole, and tetracycline was high, whereas resistance to all 5 antimicrobials (ACSSuT R-type) comprised 327 (41%) and was highly prevalent in Salmonella enterica serotype Typhimurium (72.7%), the most common serotype.
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Antimicrobial susceptibilities of Proteus mirabilis : a longitudinal nationwide study from the Taiwan surveillance of antimicrobial resistance (TSAR) program
Jann-Tay Wang,Jann-Tay Wang,Pei-Chen Chen,Shan-Chwen Chang,Yih-Ru Shiau,Hui-Ying Wang,Jui-Fen Lai,I-Wen Huang,Mei-Chen Tan,Tsai-Ling Lauderdale +9 more
TL;DR: A significant decrease in susceptibility to 3rd-generation cephalosporins and ciprofloxacin occurred in Proteus mirabilis from Taiwan in the past decade and continuous surveillance on antimicrobial resistance and associated resistance mechanisms in P. mirabilIS is warranted.
•Journal Article
Surveillance of antibiotic resistance in Taiwan, 1998.
TL;DR: For the first national surveillance of antibiotic resistance in Taiwan, 3,211 isolates from 22 hospitals were collected in 1998 and identified subpopulations with smaller diameters in the case of vancomycin against S. aureus, ciprofloxacin against E. coli, and ciprafloxACin against Salmonella spp.
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