Peder Lund
Stanford University
17 Papers
184 Citations
Peder Lund is an academic researcher from Stanford University. The author has contributed to research in topics: Biology & T cell. The author has an hindex of 7, co-authored 12 publications.
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Papers
Clonal Deletion Prunes but Does Not Eliminate Self-Specific αβ CD8+ T Lymphocytes
Wong Yu,Ning Jiang,Peter J.R. Ebert,Brian A. Kidd,Sabina Müller,Peder Lund,Jeremy Juang,Keishi Adachi,Tiffany Tse,Michael E. Birnbaum,Evan W. Newell,Darrell M. Wilson,Gijsbert M. Grotenbreg,Salvatore Valitutti,Stephen R. Quake,Mark M. Davis +15 more
TL;DR: The conclusion is that clonal deletion prunes but does not eliminate self-specific T cells and it is suggested that to do so would create holes in the repertoire that pathogens could readily exploit.
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Apoptosis and other immune biomarkers predict influenza vaccine responsiveness
David Furman,Vladimir Jojic,Brian A. Kidd,Shai S. Shen-Orr,Jordan V. Price,Justin A. Jarrell,Tiffany Tse,Huang Huang,Peder Lund,Holden T. Maecker,Paul J. Utz,Cornelia L. Dekker,Daphne Koller,Mark M. Davis,Mark M. Davis +14 more
TL;DR: Using machine learning, nine variables that predict the antibody response with 84% accuracy are identified, two of which are involved in apoptosis, which positively associated with the response to vaccination and was confirmed to be a contributor to vaccine responsiveness in mice.
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Targeting CD137 enhances the efficacy of cetuximab
Holbrook E Kohrt,A. Dimitrios Colevas,Roch Houot,Roch Houot,Kipp Weiskopf,Matthew J. Goldstein,Peder Lund,Antonia Ms Mueller,Idit Sagiv-Barfi,Aurélien Marabelle,Aurélien Marabelle,Ruth R Lira,Emily Troutner,Lori Richards,Amanda Rajapaska,Jonathan Hebb,Cariad Chester,Erin Waller,Anton Ostashko,Wen-Kai Weng,Lieping Chen,Debra K. Czerwinski,Yang Xin Fu,John B. Sunwoo,Ronald Levy +24 more
TL;DR: It is found that isolated human NK cells substantially increased expression of CD137 when exposed to cetuximab-coated, EGFR-expressing HN and CRC cell lines, and activation ofCD137 with an agonistic mAb enhanced NK cell degranulation and cytotoxicity.
Global Analysis of O-GlcNAc Glycoproteins in Activated Human T Cells.
TL;DR: These studies provide a global analysis of O-GlcNAc dynamics during T cell activation and the first characterization, to the authors' knowledge, of the O- Glc NAc glycoproteome in human T cells.
Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
Sima Khazaei,Carol C.L. Chen,Augusto Faria Andrade,Nisha Kabir,Pariya Azarafshar,Shahir M. Morcos,Josiane Alves França,Mariana Lopes,Peder Lund,Geoffroy Danieau,Samantha Worme,Lata Adnani,Nadine Nzirorera,Xiao Chen,Gayathri Yogarajah,Caterina Russo,Michele Zeinieh,Cassandra J. Wong,Laura Bryant,Steven Hebert,Bethany Tong,Tianna S. Sihota,Damien Faury,Evan Puligandla,Wajih Jawhar,Veronica Sandy,Mitra Cowan,Emily M. Nakada,Loydie A. Jerome-Majewska,Benjamin Ellezam,Carolina Cavaliéri Gomes,Jonas Denecke,Davor Lessel,Marie T. McDonald,Carolyn Pizoli,Kathryn R. Taylor,Benjamin T. Cocanougher,Elizabeth J. Bhoj,Anne-Claude Gingras,Benjamin A. Garcia,Chao Lu,Eric I. Campos,Claudia L. Kleinman,Livia Garzia,Nada Jabado +44 more
TL;DR: In this article , H3.3G34R/V/W mutants exhibited microcephaly and neurodegeneration, with abnormal accumulation of disease-associated microglia and concurrent neuronal depletion.
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