Spectrometric Identification of Organic Compounds

The pros and cons of phytoestrogens

A composition and method for facilitating the growth, protection and healing of tissues and cells in animals and humans. Formulated as a either a powder, gel, paste, film, fluid injectable, rehydratable freeze-dried paste or sponge, sprayable solution, topically applied patch with adhesive and reservoir system, an intermediate for coatables such as films and bandages, a matrix for membranes, or as a matrix of flexible polymer(s), or delivered as either an orally ingestible liquid, tablet or capsule. The main ingredients are hydrolyzed Type I collagen having a molecular weight of 1,000-10,000, polysulfated glycosaminoglycans, a hyaluronic acid salt, a glucosamine salt, and optionally, a chelated manganese ascorbate and L-malic acid. In the topical form, the composition is administered to the cleaned wound site where it absorbs exudate, provides a physical barrier to bacterial infestation, reduces pain, and expedites wound healing by having chemotactic, hemostatic, bacteriostatic, and other therapeutic benefits. Scars are advantageously reduced.

Composition and method for growing, protecting, and healing tissues and cells

Background Anemia, a morbid condition, is a global concern that affects people of all age groups. This scenario has attracted the attention of several government organizations for implementing strict regulations to provide nutritional security. Iron fortification and supplementation has been in practice from the past decades. However, there is a need for determining an effective strategy to address this rising concern among the vulnerable population. Scope and approach Among the existing approaches, iron fortification of foods remains to be cheaper and effective in targeting large-scale population without the intervention of pharmaceutical drugs. The key challenge is the bioavailability of iron from fortified foods. Thus, this work presents a comprehensive review of morbidities of anemia, causes, the significance of haem and non-haem iron, absorption, and bioavailability, in context with different iron fortification approaches. Key findings Apart from the nutritional deficit, anemia is also associated with a sedentary lifestyle linked with obesity and diabetes. The complex interaction of elemental iron and its physiology have been highlighted in consideration with potential iron enhancers and inhibitors. It was found that the incorporation of haem iron would complement the effectiveness of non-haem iron through fortification. Several iron fortification techniques focused on combating iron deficiency have been described. Conclusions Food fortification is a promising strategy for reducing the prevalence of anemia. Food vehicles must be designed considering its synergistic effects with iron complexes for effective absorption and bioavailability. However, the scalability, cost economics, safety concerns and acceptability of the iron-fortified foods remain as constraints that have to be addressed. Further, the application of novel food processing techniques with food fortification can result in the emergence of novel approaches for addressing iron deficiency and anemia.

Iron deficiency anemia: A comprehensive review on iron absorption, bioavailability and emerging food fortification approaches

It is well established that, over the course of development, hormones shape the vertebrate brain such that sex specific physiology and behaviors emerge. Much of this occurs in discrete developmental windows that span gestation through the prenatal period, although it is now becoming clear that at least some of this process continues through puberty. Perturbation of this developmental progression can permanently alter the capacity for reproductive success. Wildlife studies have revealed that exposure to endocrine disrupting compounds (EDCs), either naturally occurring or man made, can profoundly alter reproductive physiology and ultimately impact entire populations. Laboratory studies in rodents and other species have elucidated some of the mechanisms by which this occurs and strongly indicate that humans are also vulnerable to disruption. Use of hormonally active compounds in human medicine has also unfortunately revealed that the developing fetus can be exposed to and affected by endocrine disruptors, and that it might take decades for adverse effects to manifest. Research within the field of environmental endocrine disruption has also contributed to the general understanding of how early life experiences can alter reproductive physiology and behavior through non-genomic, epigenetic mechanisms such as DNA methylation and histone acetylation. These types of effects have the potential to impact future generations if the germ line is affected. This review provides an overview of how exposure to EDCs, particularly those that interfere with estrogen action, impacts reproductive physiology and behaviors in vertebrates.

/pdf/long-term-effects-of-environmental-endocrine-disruptors-on-339ebqlrjt.pdf

Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior.

A method for the estimation of protein in anhydrous milk fat is described. The protein concentration is estimated by quantifying the arginine and aspartic acid (ASX) released upon acid hydrolysis of the anhydrous milk fat. Arginine and aspartic acid are derivatized with the fluorescent tag 9-fluorenylmethoxycarbonyl (FMOC), the derivatives are quantified by reversed phase HPLC, and the protein concentration in the anhydrous milk fat is estimated as 8.77 × (Arg + ASX). Method suitability was defined by experimental assessments of FMOC-arginine and FMOC-aspartic acid linearity (R
 2 averages > 0.999), protein estimate precision [day-to-day RSD values (n = 8 days) ranged from 7.3 to 14 % for protein concentrations of 9.42 to 40.0 mg/kg of anhydrous milk fat], protein estimate accuracy [spike recovery average = 95.6 % (9.3 %), n = 8, spiking level = 20 mg/kg and agreement of the experimental protein estimate for butter, 0.611 (0.044) g/100 g, n = 3 lots, with a published value 0.6/100 g], and analyte selectivity (baseline resolution of FMOC-arginine and FMOC-aspartic acid from the FMOC derivatives of other common amino acids). The method provides for a reliable estimation of the protein content of anhydrous milk fat, when present at concentrations >2 mg/kg.

Estimation of Protein in Anhydrous Milk Fat

Disclosed herein is a nutrient delivery system. The nutrient delivery system includes a pod and a nutritional powder for use in providing a nutritional formula.

Nutrient delivery system

Disclosed are nutritional compositions and methods for preparing the compositions, comprising fat, protein, and carbohydrate, including a combination of curcumin, demethoxycurcumin, and bisdemethoxycurcumin, which combination is solubilized in a polar oil having an HLB value of from about 0.7 to about 14 wherein the weight ratio of the bisdemethoxycurcumin to the curcumin is from about 1:1 to about 1:7 and the weight ratio of the bisdemethoxycurcumin to the demethoxycurcumin is from about 1:1 to about 1:2.5. The composition provides a selected ratio of curcuminoids having improved biological activity, bioavailability, and reduced color impact.

Methods for Making Nutritional Compositions Comprising Curcuminoids

Disclosed herein is a nutrient delivery system comprising a pod and a nutritional powder. The nutritional powder includes at least one hydrolyzed protein and at least one masking agent to reduce any bitterness associated with the resulting nutritional formula.

Nutrient delivery system with hydrolyzed proteins

Evaluations of protein-metal association in nutritional products

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