Paul J Kim
University of California, San Diego
15 Papers
23 Citations
Paul J Kim is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Ischemic cardiomyopathy & Induced pluripotent stem cell. The author has an hindex of 4, co-authored 15 publications. Previous affiliations of Paul J Kim include University of California & Cardiovascular Institute of the South.
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Papers
Direct Evaluation of Myocardial Viability and Stem Cell Engraftment Demonstrates Salvage of the Injured Myocardium
Paul J Kim,Morteza Mahmoudi,Xiaohu Ge,Yuka Matsuura,Ildiko Toma,Scott A. Metzler,Nigel G. Kooreman,John Ramunas,Colin Holbrook,Michael V. McConnell,Helen M. Blau,Phillip Harnish,Eric Rulifson,Phillip C. Yang +13 more
TL;DR: The functional restoration seen in MiPSCs was characterized by increased myocardial viability and sustained engraftment without de novo cardiac differentiation, indicating salvage of the injured myocardium.
Telmisartan in the diabetic murine model of acute myocardial infarction: dual contrast manganese-enhanced and delayed enhancement MRI evaluation of the peri-infarct region
Ildiko Toma,Paul J Kim,Rajesh Dash,Michael V. McConnell,Dwight G. Nishimura,Phillip Harnish,Phillip C. Yang +6 more
TL;DR: The improved cardiac function in ischemic cardiomyopathy of diabetic mice by telmisartan is attributed to the attenuation of the peri-infarct injury by the angiogenic effects of EPCs to salvage the injuredCardiomyocytes.
Manganese-enhanced MRI detects live human amnion-derived mesenchymal stem cells in vivo after transplantation and restoration of myocardial function in a pig ischemia-reperfusion injury model
Rajesh Dash,Ildiko Toma,Fumiaki Ikeno,Jennifer Lyons,Shahriar Heidary,Marie-Claude Parent,I-Ning E. Wang,Xiaohu Ge,Jaehoon Chung,Justin Lam,Paul J Kim,Kaori Nakagawa,Svetlana Lyalina,Grace Do,Robert C. Robbins,Michael V. McConnell,Alan C. Yeung,Phillip Harnish,Phillip C. Yang +18 more
TL;DR: Human Amnion-derived Mesenchymal Stem Cells were transplanted into the infarct and periinfarct regions of a pig ischemia-reperfusion model and improved cardiac systolic function post-MI, and Cardiac MRI with Manganese-Enhanced MRI was able to detect increased CNR from live populations of hAMSCs.
Advances and New Insights in Post-Transplant Care: From Sequencing to Imaging
TL;DR: Developments in imaging and sequencing techniques in the application of heart-transplant research are improving rapidly and in parallel with improvements in analysis of these large datasets, resulting in new mechanistic patterns that can be combined with traditional hypothesis testing.
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