Paul B. Rainey
Max Planck Society
235 Papers
1.2K Citations
Paul B. Rainey is an academic researcher from Max Planck Society. The author has contributed to research in topics: Biology & Pseudomonas fluorescens. The author has an hindex of 70, co-authored 222 publications. Previous affiliations of Paul B. Rainey include Massey University & Mansfield University of Pennsylvania.
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Papers
Adaptive evolution by spontaneous domain fusion and protein relocalization
TL;DR: It is shown that an adaptive phenotype is caused by the emergence of a new gene by domain fusion and protein relocalization in Pseudomonas.
Dual Involvement of CbrAB and NtrBC in the Regulation of Histidine Utilization in Pseudomonas fluorescens SBW25
Xue-Xian Zhang,Paul B. Rainey +1 more
TL;DR: The data show that CbrAB plays a role in regulation of both carbon and nitrogen catabolism and maintains activity of catabolic pathways under different C:N ratios.
Case Studies of the Spatial Heterogeneity of DNA Viruses in the Cystic Fibrosis Lung
Dana Willner,Matthew Haynes,Mike Furlan,Nicole Hanson,Breeann Kirby,Yan Wei Lim,Paul B. Rainey,Robert Schmieder,Merry Youle,Douglas Conrad,Forest Rohwer +10 more
TL;DR: It is postulate that viral communities in CF lungs are spatially distinct and contribute to CF pathology by augmenting the metabolic potential of resident microbes, as well as by directly damaging lung tissue via carcinomas and herpesviral outbreaks.
Cheats as first propagules: a new hypothesis for the evolution of individuality during the transition from single cells to multicellularity.
Paul B. Rainey,Benjamin Kerr +1 more
TL;DR: The emergence of individuality during the evolutionary transition from single cells to multicellularity poses a range of problems, and the evolution of a means of collective reproduction is not a trivial issue, requiring careful consideration of mechanistic details as discussed by the authors.
Bistability in a Metabolic Network Underpins the De Novo Evolution of Colony Switching in Pseudomonas fluorescens
Jenna Gallie,Eric Libby,Frederic Bertels,Philippe Remigi,Christian Bille Jendresen,Gayle C. Ferguson,Nicolas Desprat,Marieke F. Buffing,Uwe Sauer,Hubertus J. E. Beaumont,Jan Martinussen,Mogens Kilstrup,Paul B. Rainey +12 more
TL;DR: It is established that capsule switching results from perturbation of the pyrimidine biosynthetic pathway, and a simple mathematical model is presented demonstrating that the molecular components of the decision point are capable of producing switching.