Patrick Lemoine
6 Papers
1 Citations
Patrick Lemoine is an academic researcher. The author has contributed to research in topics: Primary Insomnia & Melatonin. The author has an hindex of 5, co-authored 6 publications.
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Papers
Prolonged‐release melatonin improves sleep quality and morning alertness in insomnia patients aged 55 years and older and has no withdrawal effects
TL;DR: PR‐melatonin is the first drug shown to significantly improve quality of sleep and morning alertness in primary insomnia patients aged 55’years and older, suggesting more restorative sleep, and without withdrawal symptoms upon discontinuation.
Prolonged-release melatonin for insomnia – an open-label long-term study of efficacy, safety, and withdrawal
TL;DR: Results support the efficacy and safety of PRM in primary insomnia patients aged 20–80 throughout 6–12 months of continuous therapy.
Efficacy and safety of prolonged-release melatonin for insomnia in middle-aged and elderly patients with hypertension: a combined analysis of controlled clinical trials
Patrick Lemoine,Alan G Wade,Amnon Katz,Tali Nir,Nava Zisapel +4 more
- 25 Jan 2012
TL;DR: Quality of sleep and behavior following wakening improved significantly with PRM compared with placebo, and PRM appears to be safe for insomnia in patients with cardiovascular comorbidity.
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Efficacy and Safety of Circadin® in the Treatment of Primary Insomnia
Nava Zisapel,Patrick Lemoine +1 more
TL;DR: PR-melatonin 2mg is a first-class medicine that goes beyond the facilitation of sleep onset of other widely used drugs for insomnia and can be used concomitantly with most medications, but potentiates the hypnotic effects of gamma-aminobutyric acid receptor modulators.
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Prolonged-release melatonin for the treatment of insomnia: targeting quality of sleep and morning alertness
TL;DR: Prolonged-release (PR) melatonin (Circadin ®, Neurim Pharmaceuticals, Tel-Aviv, Israel) is a nonbenzodiazepine licensed to treat primary insomnia in patients aged 55 years and older and has been shown to be effective in improving quality of sleep and morning alertness.