Patrick Kollmann
Technische Universität München
4 Papers
6 Citations
Patrick Kollmann is an academic researcher from Technische Universität München. The author has contributed to research in topics: Downregulation and upregulation & TRPV1. The author has an hindex of 4, co-authored 4 publications.
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Papers
Submucosal enteric neurons of the cavine distal colon are sensitive to hypoosmolar stimuli
Patrick Kollmann,Kristin Elfers,Stefanie Maurer,Martin Klingenspor,Michael Schemann,Gemma Mazzuoli-Weber +5 more
TL;DR: Results show that submucosal neurons respond to hypoosmolar stimuli with increased activity which is partially mediated by the transient receptor potential vanilloid 4 channel and is fundamental to better explain the nerve‐mediated control of the gastrointestinal functions during physiological and pathophysiological conditions.
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Sensitivity Testing in Irritable Bowel Syndrome With Rectal Capsaicin Stimulations: Role of TRPV1 Upregulation and Sensitization in Visceral Hypersensitivity?
Sander van Wanrooij,Mira M. Wouters,Lukas Van Oudenhove,Winde Vanbrabant,Stephanie Mondelaers,Patrick Kollmann,Florian Kreutz,Michael Schemann,Guy E. Boeckxstaens +8 more
TL;DR: Increased pain perception was significantly associated with anxiety and VH, symptoms scores of abdominal pain, loose stools, and stool frequency, and TRPV1 expression levels did not correlate with pain perception to capsaicin or clinical symptoms in IBS patients or the subgroups.
Three-Dimensional Gastrointestinal Organoid Culture in Combination with Nerves or Fibroblasts: A Method to Characterize the Gastrointestinal Stem Cell Niche
Agnieszka Pastula,Moritz Middelhoff,Anna Brandtner,Moritz Tobiasch,Bettina Höhl,Andreas H. Nuber,Ihsan Ekin Demir,Steffi Neupert,Patrick Kollmann,Gemma Mazzuoli-Weber,Michael Quante +10 more
TL;DR: Different 3D culture systems to culture gastrointestinal epithelium are described that should enable us to study the stem cell niche in vitro in the future: organoid culture and multilayered systems such as organotypic cell culture and culture of intestinal tissue fragments ex vivo.
Properties of myenteric neurones and mucosal functions in the distal colon of diet-induced obese mice.
François Reichardt,Charlotte Baudry,Lisa Gruber,Gemma Mazzuoli,Raphaël Moriez,Christian Scherling,Patrick Kollmann,Hannelore Daniel,Sigrid Kisling,Dirk Haller,Michel Neunlist,Michael Schemann +11 more
TL;DR: It is concluded that enhanced neural excitation in the colon by acetylcholine and serotonin is a key feature of a later phase of obesity and is involved in altered ENS functions and abnormal colonic transit.