Patrick J. Boyle
University of New Mexico
47 Papers
686 Citations
Patrick J. Boyle is an academic researcher from University of New Mexico. The author has contributed to research in topics: Hypoglycemia & Diabetes mellitus. The author has an hindex of 26, co-authored 43 publications. Previous affiliations of Patrick J. Boyle include University of Oregon & New Mexico Highlands University.
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Papers
Brain glucose uptake and unawareness of hypoglycemia in patients with insulin-dependent diabetes mellitus.
TL;DR: During hypoglycemia, patients with IDDM who have nearly normal glycosylated hemoglobin values have normal glucose uptake in the brain, which preserves cerebral metabolism, reduces the responses of counterregulatory hormones, and causes an unawareness of hypoglyCEmia.
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Diminished brain glucose metabolism is a significant determinant for falling rates of systemic glucose utilization during sleep in normal humans.
Patrick J. Boyle,James C. Scott,Andrew J. Krentz,Roger J. Nagy,Eileen Comstock,Charles Hoffman +5 more
TL;DR: A decline in brain glucose metabolism is a significant determinant of falling rates of systemic glucose utilization during sleep, and was more closely linked to duration of sleep.
Effects of pioglitazone and rosiglitazone on blood lipid levels and glycemic control in patients with type 2 diabetes mellitus: a retrospective review of randomly selected medical records.
Patrick J. Boyle,Allen B. King,Leann Olansky,Albert Marchetti,Helen Lau,Raf Magar,John Martin +6 more
TL;DR: Treatment with piog litazone was associated with greater beneficial effects on blood lipid levels than treatment with rosiglitazone, whereas glycemic control was equivalent between the 2 treatments.
170
Managing type 2 diabetes: going beyond glycemic control.
TL;DR: It has been suggested that TZDs, when used either as add-on therapy or when appropriate as monotherapy, may conserve pancreatic beta-cell function over an observed 3- to 5-year period of time and sustain a decrease in A1C ranging from 0.5%-1.5%.
102
Octreotide reverses hyperinsulinemia and prevents hypoglycemia induced by sulfonylurea overdoses.
TL;DR: It is concluded that octreotide is safe and effective and should be strongly considered as a logical therapeutic alternative for this metabolic emergency and in four of eight subjects entirely eliminated the need for exogenous glucose after a large overdose of glipizide.
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