Background The number of people with undiagnosed, untreated, and uncontrolled hypertension is higher in Ethiopia. This in turn increases the risk of developing complications and hospitalization. This study aimed to assess the prevalence of hypertension complication hospitalization among medical admissions and admission outcomes of hypertension complication patients in the medical ward of Saint Peter Specialized Hospital, Addis Ababa. Methods We used a hospital-based cross-sectional study. Data were collected by reviewing all medical ward admission logbook records from January 1st, 2018 to December 30th, 2019. An individual patient folder of 308 patients admitted due to hypertension complications was selected for further detailed investigation and then entered into Epi Data version 3.1 and exported to SPSS version 24 statistical software for analysis. Results Of the total 2728 medical admissions, 308 (11.3%) were patients with hypertension complications. Hypertension complications account for 308 (11.3%) of all medical admissions. Their mean age and length of hospital stay were 59.85 (± 16.36) years and 11.45 (± 11.48) days, respectively. Near to two-third of 196 (63.6%) of them were stroke patients followed by 76 (24.7%) heart disease. Fifty-two (16.9%) hypertension complication patients died at admission which accounts for 52 (14.6%) of all medical ward deaths. As age increases, the risk of death at admission increases by 6.5%. Similarly, the risk of death increased by three-fold for a month increase in the duration of anti-hypertensive drug discontinuation. Rural residents had a 3.5% lesser risk of death than urban patients. Conclusion Hypertension complications had a significant share of the medical ward mortality rate. Cerebrovascular and cardiovascular complications were common causes of hospitalization and inpatient death. Old age, urban residence, and prolonged duration of anti-hypertensive drug discontinuation increased the risk of death at admission.

/pdf/admission-and-inpatient-mortality-of-hypertension-2y0cecxzu1.pdf

Admission and Inpatient Mortality of Hypertension Complications in Addis Ababa

Few data from sub-Saharan Africa exist on the effects of hypertension on the organs of the human body. We aimed to establish the prevalence of hypertensive end organ damage (EOD) in an elderly cohort of Tanzanians. The population aged 70 years and over of 2 villages in northern Tanzania (n = 246), had blood pressure (BP) data available from 2010 and 2013, and underwent in-depth follow-up for markers of hypertensive EOD in 2016. Assessment included ankle-brachial pressure index, lying-standing BP, electrocardiogram, and mid-stream urine dip. Sustained hypertension (those with hypertension at all 3 assessments) was found in 129 (52.4% subjects). Of the entire cohort, 13.9% had left ventricular hypertrophy and 26.4% had peripheral arterial disease, both of which were associated with sustained hypertension, although orthostatic hypotension, stroke, proteinuria, and arterial stiffening were not. Further investigation, particularly in younger age groups, is merited if hypertension-associated morbidity is to be controlled.

https://onlinelibrary.wiley.com/doi/pdf/10.1111/jch.13187

Hypertension in a resource-limited setting: Is it associated with end organ damage in older adults in rural Tanzania?

Background Addis Ababa University is one of the thirteen medical schools (in twelve countries) in Africa that are recipients of the Medical Education Partnership Initiative (MEPI). MEPI- Ethiopia is a consortia project that involved four Ethiopian medical schools (Addis Ababa, Defense Medical College, Haramaya , and Hawassa) as well as US partner Universities: Alabama, Emory, John Hopkins, California-San Diego, and Wisconsin. With a funding source  from  the  Office of the U.S. Global AIDS Coordinator (OGAC) and the Health Resources and Service Administration (HRSA). Operating with focus under three strategic objectives (improvement of medical education, human capacity building and retention, and enhancement of research and bioethics capacity), the program strives to improve medical education and retention of the health workforce consistent with the mission of the Federal Ministries of Health and Education, which overall will significantly impact the health status of Ethiopians Key accomplishments : Strategic objective1: Improvement of the Medical Education System to manage the increased class size, MEPI supports a small class teaching approach;Provision of teaching aids and learning resources including skills labs, textbooks, microscopes, and other resources; Information Technology (IT) infrastructure enhancement and e-Learning system implementation: Strategic objective 2: Human capacity building and faculty retention ; Scale up of research support for graduates working in remote areas: ‘ Strategic objective 3: Enhancement of research and bioethics capacity : With the supportive supervision of their mentors, the first cohort of 10 undergraduate medial students have completed their research activities and are on the process of developing disseminating results and developing manuscripts for publication.Research culture is being developed among junior medical students ; Furthermore, MEPI supported the establishment of the AAU CHS Office of Research Administration (ORA) that serves as the operational wing of the Office of the Associate Director for Research and Technology Transfer.

Medical Education Partnership (MEPI), Ethiopia: Objectives and overview of key accomplishments.

274 Background: Complications due to undetected and uncontrolled hypertension have been recorded to be devastating. Among these are cerebrovascular, cardiovascular and renal complications. Lack of data on the patterns of these complications, combined with the notion that hypertension is only a problem of developed nations, has resulted in missed opportunities for early detection and treatment. Method: A retrospective cross-sectional study was performed through medical chart review of 106 hypertension patients who were admitted with complications of hypertension at Tikur Anbessa Specialized Hospital from January 2013 to January 2014 E.C. Results: A total of 106 medical charts of hypertensive patients were reviewed. Among the patients involved in the study, 51% were male, 45% were in their fifth and sixth decades and two third of them did not have any co morbidity. Sixty seven percent of these patients had cerebrovascular disease (stroke), 11% had stroke and hypertensive heart disease, 8% had stroke, hypertensive heart disease and chronic kidney disease (all three), and 5% had stroke with chronic kidney disease. However, there was no significant association between the considered variables and the outcome. Conclusion: This study has revealed most of the patients have stroke as a complication, therefore preventive or prophylactic measures should be encouraged to avail it. Keywords: Hypertension, Stroke, Tikur Anbessa Specialized Hospital

Patterns of complications seen in patients with hypertension admitted to tikur anbessa hospital: a retrospective analysis.

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Patterns of complications seen in patients with hypertension admitted to tikur anbessa hospital: a retrospective analysis.