Patrick Duriez
university of lille
49 Papers
638 Citations
Patrick Duriez is an academic researcher from university of lille. The author has contributed to research in topics: Apolipoprotein B & Cholesterol. The author has an hindex of 22, co-authored 49 publications. Previous affiliations of Patrick Duriez include French Institute of Health and Medical Research & Lille University of Science and Technology.
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Papers
PPAR: a new pharmacological target for neuroprotection in stroke and neurodegenerative diseases.
Régis Bordet,Thavarak Ouk,Olivier Pétrault,Patrick Gelé,Sophie Gautier,M. Laprais,Dominique Deplanque,Patrick Duriez,Bart Staels,Jean-Charles Fruchart,Michèle Bastide +10 more
TL;DR: Beyond neuroprotection in cerebral ischaemia, PPARs are also pertinent pharmacological targets to induce neuro protection in chronic neurodegenerative diseases.
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Apolipoprotein A-II, HDL metabolism and atherosclerosis
TL;DR: It can be suggested that apo A-II is not a strong determinant of lipid metabolism, but is rather a modulator of reverse cholesterol transport, which might improve reverse cholesterol Transport and might reduce atherosclerosis development while some other effects might be deleterious.
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The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential
Jean-Charles Fruchart,Raul D. Santos,Carlos A. Aguilar-Salinas,Masanori Aikawa,Khalid Al Rasadi,Pierre Amarenco,Philip J. Barter,Richard Ceska,Alberto Corsini,Jean-Pierre Després,Patrick Duriez,Robert H. Eckel,Marat V. Ezhov,Michel Farnier,Henry N. Ginsberg,Michel P. Hermans,Shun Ishibashi,Fredrik Karpe,Tatsuhiko Kodama,Wolfgang Koenig,Wolfgang Koenig,Michel Krempf,Michel Krempf,Soo Lim,Alberto J. Lorenzatti,Ruth McPherson,Jesús Millán Núñez-Cortés,Børge G. Nordestgaard,Børge G. Nordestgaard,Hisao Ogawa,Chris J. Packard,Jorge Plutzky,Carlos I. Ponte-Negretti,Aruna D. Pradhan,Aruna D. Pradhan,Kausik K. Ray,Željko Reiner,Paul M. Ridker,Massimiliano Ruscica,Shaukat Sadikot,Hitoshi Shimano,Piyamitr Sritara,Jane K Stock,Ta-Chen Su,Andrey V. Susekov,André Tartar,Marja-Riitta Taskinen,Alexander Tenenbaum,Alexander Tenenbaum,Lale Tokgozoglu,Brian Tomlinson,Anne Tybjærg-Hansen,Anne Tybjærg-Hansen,Paul Valensi,Michal Vrablík,Walter Wahli,Walter Wahli,Walter Wahli,Gerald F. Watts,Shizuya Yamashita,Koutaro Yokote,Alberto Zambon,Peter Libby +62 more
TL;DR: In this paper, the authors developed a selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) for the treatment of atherogenic dyslipidemia.
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Paraoxonase activity is reduced by a pro-atherosclerotic diet in rabbits.
Michael I. Mackness,Agnes Bouiller,Nathalie Hennuyer,Bharti Mackness,Maxine Hall,Anne Tailleux,Patrick Duriez,Bernard Delfly,Paul N. Durrington,Jean-Charles Fruchart,Nicolas Duverger,Jean-Michel Caillaud,Graciela Castro +12 more
TL;DR: The relationship between PON1 and atherosclerosis development in transgenic rabbits overexpressing human apolipoprotein (apo) A-I and nontransgenic littermates fed a pro-atherogenic diet is examined.
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Antipsychotic drug action on SREBPs-related lipogenesis and cholesterogenesis in primary rat hepatocytes
Emilie Lauressergues,Bart Staels,Karine Valeille,Zouher Majd,Dean W. Hum,Patrick Duriez,Didier Cussac +6 more
TL;DR: Inductions of lipid and cholesterol synthesis observed with clozapine and olanzapine were also associated with up-regulation of the transcription factors sterol regulatory element-binding protein (SREBP)-1 and/or SREBP-2 and their associated target genes.
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