Patrick Chang
Georgia Institute of Technology
10 Papers
Patrick Chang is an academic researcher from Georgia Institute of Technology. The author has contributed to research in topics: Finite element method & Lattice (order). The author has an hindex of 7, co-authored 8 publications. Previous affiliations of Patrick Chang include Parker H. Petit Institute for Bioengineering & Bioscience.
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Papers
Frustrated Phagocytic Spreading of J774A-1 Macrophages Ends in Myosin II-Dependent Contraction.
Daniel T. Kovari,Wenbin Wei,Patrick Chang,Jan-Simon Toro,Ruth Fogg Beach,Dwight M. Chambers,Karen Porter,Doyeon Koo,Jennifer E. Curtis +8 more
TL;DR: It is found that late-stage contraction initiates after the cell surface area increases by 225%, which is consistent with the point at which cortical tension begins to rise, and reducing tension by exposing cells to hypertonic buffer shifts the onset of contraction to occur in larger contact areas.
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The Size Matching and Scaling Method: A Synthesis Method for the Design of Mesoscale Cellular Structures
Patrick Chang,David W. Rosen +1 more
- 13 Dec 2010
TL;DR: This paper presents a new, highly efficient, method for the design of mesoscale lattice structures, the Size Matching and Scaling method, which eliminates the need for time-consuming optimization by using a combination of a solid-body finite element analysis and a library of pre-defined lattice configurations to generate a structure's lattice topology.
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Cell Surface Access Is Modulated by Tethered Bottlebrush Proteoglycans.
Patrick Chang,Patrick Chang,Louis T. McLane,Louis T. McLane,Louis T. McLane,Ruth Fogg,Ruth Fogg,Jan Scrimgeour,Jan Scrimgeour,Jan Scrimgeour,Johnna S. Temenoff,Johnna S. Temenoff,Anna Granqvist,Anna Granqvist,Jennifer E. Curtis,Jennifer E. Curtis +15 more
TL;DR: Cell equipped with hyaluronan-rich PCM can in principle manipulate surface accessibility or sequestration of molecules by tuning the bottlebrush proteoglycan content to alter PCM porosity and the number of electrostatic binding sites.
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Developing a Bio-Inspired Design Repository Using Ontologies
Jamal O. Wilson,Patrick Chang,Sungshik Yim,David W. Rosen +3 more
- 01 Jan 2009
TL;DR: This paper presents a design repository for storing and retrieving biological (and engineering) design strategies, and demonstrates that subsumption allows precise retrieval of relevant biological strategies from the repository.
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An Improved Size, Matching, and Scaling Method for the Design of Deterministic Mesoscale Truss Structures
Patrick Chang,David W. Rosen +1 more
- 01 Jan 2011
TL;DR: In this paper, a modified size matching and scaling design method was presented that addresses key issues in the original size matching method and expands the library of configurations in order to improve lattice performance.
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